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Example sentences for: sbhms
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This is clearly a derived state because the SBHM originally evolved through the duplication of a single ancestral unit that contained an intact "waist"-like loop between strands 2 and 3. The form of the SBHM with a shortened loop in the first internal repeat is additionally seen in several bacterial-specific families of SBHMs.
The wide spread in different phylogenetic lineages of two other SBHM domains, namely those found in dihydrolipoamide acetyltransferase and the glycine-cleaving enzyme, is indicative of their presence in LUCA [ 76 ] . The SBHM of the DDRPs is specifically related to the biotin/lipoate-binding SBHMs.
This two-domain module is inserted precisely in the same region as the C-terminal SBHMs seen in the bacterial lineage (Fig.
Streptococcus β subunit, E = 10 -4, iteration 2) well before the classical SBHMs (eg.
Similarly, the β' subunit of proteobacteria, Aquifex , spirochaetes, cyanobacteria and chlamydiae contains an additional set of SBHMs C-terminal of the DPBB domain, preceding the C-terminal SBHM that is shared by all bacteria (Fig.
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