Words similar to sbhm
Example sentences for: sbhm
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From such a precursor, which existed prior to LUCA, the SBHM domain apparently diversified into two forms, one that covalently bound organic radicals, and another that specialized in non-covalent interactions with proteins or nucleic acids.
The β and β' subunits of the bacterial DDRP are the only proteins that contain both versions of the SBHM (Fig.
Notably, this is the same set of bacteria that contain extra SBHM domains inserted in the C-terminal region of the β' subunit (Fig.
A PSI-BLAST search started with the N-terminal SBHM from the Aquifex aeolicus DDRP β' subunit detected several SBHMs from proteins other than the β' subunit, such as acetylornithine deacetylase (E = 2 × 10 -7, iteration 2), the C-terminal region of bacterial cytochrome F (E = 10 -4, iteration 2), biotin carboxyl carrier domain of biotin transcarboxylases (E = 6 × 10 -4, iteration 2) and the phosphotransferase system enzyme II (E = 10 -3, iteration 2).
This is clearly a derived state because the SBHM originally evolved through the duplication of a single ancestral unit that contained an intact "waist"-like loop between strands 2 and 3. The form of the SBHM with a shortened loop in the first internal repeat is additionally seen in several bacterial-specific families of SBHMs.