Words similar to saturable
Example sentences for: saturable
How can you use “saturable” in a sentence? Here are some example sentences to help you improve your vocabulary:
[ 20 ] which includes a metabolic component that is saturable and inactivates.
Thiamine entry into mammalian cells occurs by a saturable, high affinity transporter that is deficient in humans with thiamine-responsive megaloblastic anemia (TRMA) [ 7 8 9 10 11 12 ] . Thiamine uptake by mitochondria has been demonstrated [ 13 ] , yet thiamine diphosphokinase is cytosolic and mitochondria cannot convert thiamine to ThDP [ 14 15 16 ] . Barile and coworkers demonstrated saturable uptake of ThDP by rat liver mitochondria characterized by a K m of around 20 μM.
Although mitochondria from lymphoblasts (above) and other mammalian cells [ 13 ] were found to take up thiamine, the physiological significance of the uptake is unknown given that thiamine diphosphokinase is cytosolic and mitochondria cannot convert thiamine to ThDP [ 14 16 21 ] . We thus were interested in uptake of ThDP by mitochondria, a possibility demonstrated previously with rat liver [ 14 ] . Mitochondria from normal human lymphoblasts were able to take up ThDP in a saturable, biphasic manner (fig.
We have previously reported that it takes from 12-16 h following 1,25-dihydroxyvitamin D treatment of Caco-2 cells to first appreciate an increase in saturable transcellular calcium transport [ 19 ] . This temporal response is similar to the 8-16 h observed for the achievement of maximal rates of intestinal calcium absorption in vivo following 1,25-dihydroxyvitamin D treatment of vitamin D-deficient chickens [ 28 ] . Future studies of the time course of CaT1 protein expression and localization of this protein to the brush border will be necessary to confirm this point, but must await the development of a suitable CaT1 antibody.
The uptake of bile acids by the CHO.asbt cells was saturable with an apparent K m ranging between 22 to 25 μM (Figure 3C).
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