Example sentences for: saturable

How can you use “saturable” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have previously reported that it takes from 12-16 h following 1,25-dihydroxyvitamin D treatment of Caco-2 cells to first appreciate an increase in saturable transcellular calcium transport [ 19 ] . This temporal response is similar to the 8-16 h observed for the achievement of maximal rates of intestinal calcium absorption in vivo following 1,25-dihydroxyvitamin D treatment of vitamin D-deficient chickens [ 28 ] . Future studies of the time course of CaT1 protein expression and localization of this protein to the brush border will be necessary to confirm this point, but must await the development of a suitable CaT1 antibody.

  • The uptake of bile acids by the CHO.asbt cells was saturable with an apparent K m ranging between 22 to 25 μM (Figure 3C).

  • Thiamine entry into mammalian cells occurs by a saturable, high affinity transporter that is deficient in humans with thiamine-responsive megaloblastic anemia (TRMA) [ 7 8 9 10 11 12 ] . Thiamine uptake by mitochondria has been demonstrated [ 13 ] , yet thiamine diphosphokinase is cytosolic and mitochondria cannot convert thiamine to ThDP [ 14 15 16 ] . Barile and coworkers demonstrated saturable uptake of ThDP by rat liver mitochondria characterized by a K m of around 20 μM.

  • The putative rabbit EP 2 receptor was pharmacologically characterized using membranes from COS-1 cells transiently transfected with a rabbit EP2 expression vector, pcDNA3/REP 2 . Membranes from EP 2 receptor transfected COS-1 cells, exhibited saturable [ 3H]PGE 2 binding with a dissociation constant of 19.

  • Mitochondria isolated from TRMA lymphoblasts took up ThDP in an essentially identical saturable, biphasic fashion as uptake by normal mitochondria (fig.


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