Words similar to rβ
Example sentences for: rβ
How can you use “rβ” in a sentence? Here are some example sentences to help you improve your vocabulary:
Several signaling events, including the activation of Jak kinases 1 and 3 are shared among the 'common γ chain' cytokines [ 50 ] . Other signaling events, such as the activation of Shc, Gab2, SHP-2 and MAPK, are shared among IL-2 and 15, but not the other common γ chain cytokine receptors, and Tyr 388 of IL-2Rβ appears critical for these events [ 51 ] . Despite these signaling similarities, it is clear that the biological properties of IL-2 are unique among the common γ chain cytokines, as the other cytokines cannot compensate for IL-2 in the IL-2 knockout mouse [ 52 ] . In addition, IL-15 appears uniquely critical for the development of NK cells, as evidenced by the phenotypes of IL-15 [ 53 ] and IL-15R α [ 54 ] deficient mice.
Different functional subsets of genes were identified that included those for several chemokines (GRO-1, MIG, MCP-1, MCP-3, MIP1-α, MIP-β, PARC, IL-8), cytokine receptors (C-CR-1, IL-R, IL-1R antagonist, IL-2Rβ, transforming growth factor-β receptor (TGFβR), IFNγR α chain), adhesion molecules associated with mononuclear cell migration (CD62L, VCAM-1, CD64, CD29), cytotoxic proteins in granules produced by activated monocytes (grancalcin and calgranulin) and several genes associated with IFN-γ activity, such as HLA class II molecules and IFN-regulatory or responsive genes such as those for MxA, MxB and IRF-1.
Genes for chemokines and cytokines related to inflammatory processes (IP-10, MIP-1β, MCP1, MCP-3, GM-CSF/IL-15/IL-3Rβ, IL-1 receptor) showed a concordant early upregulation in vitro and in vivo.
Loading...