Words similar to ryr

Example sentences for: ryr

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Interactions between these two modules are likely to be critical for intramembrane charge movements in the assembled four-repeat channel and for coupling the movement of the S4 gating charges to the opening of the RyR1 channel.
Hence the signaling mechanism, like that reported in normal myotubes and dysgenic myotubes expressing wt-α 1S , was Ca 2+entry independent [ 29 ] . We also expressed fs-α 1S in cultured myotubes from two available gene knock-out (KO) mice, lacking the endogenous β1a isoform of the skeletal muscle DHPR [ 30 ] and lacking RyR1 [ 31 ] . As shown in Fig.
Except for the magnitude, the SR Ca 2+release signal expressed by fs-α 1S was entirely typical of skeletal myotubes with sigmoidal voltage-dependence, proceeding in the absence of external Ca 2+and requiring RyR1.
4B, we failed to detect EC coupling in these KO cells transfected with fs-α 1S . In summary, the EC coupling expressed by fs-α 1S is strictly skeletal-type and requires RyR1 and DHPR β1a.
For example, a region of RyR1 has been shown to be essential for L-type Ca 2+current expression [ 38].