Words similar to runt
Example sentences for: runt
How can you use “runt” in a sentence? Here are some example sentences to help you improve your vocabulary:
Since the nematode sequence and one of the spider sequences ( run-2 ) only contain part of the runt domain, these were not used in the phylogenetic analysis.
The amino acid sequences of the Runt domains of all each of the collected genes, together with two previously described sequences from the spider Cupiennius salei [ 15 ] , a sequence from the crayfish Pacifastacus leniusculus , and one from the nematode Meloidogyne hapla , were aligned using Clustal W [ 16 ] , as shown in Figure 2. Functionally, the Runt domain is required both for DNA binding and for interaction with its heterodimeric partner (the beta subunit), which serves to allosterically enhance the DNA binding of the Runt domain [ 1 14 ] . Superposition of the alignment and the known crystal structure of mouse Runx1 [ 14 17 ] reveals that residues that make either direct or indirect contact with DNA are invariant (marked by asterisks in Fig.
DmLozenge and DmRunxB ) or two ( DmRunxA ) introns separating exons N-terminal to the Runt domain, but all of these have different positions, and were thus likely to have been incorporated subsequent to the divergence of these genes.
Three Runt domain genes in the A. gambiae genome and two previously unidentified Runt domain genes in the D. melanogaster genome were found by TBLASTN search using the S. purpuratus Runt protein sequence as the query.
This Runx sequence is functionally involved in minor groove interactions and DNA bending by the Runt domain [ 14 ] . An important difference between it and bona fide P-loops is that the latter are invariably followed by an α-helix, whereas the structure of the Runt domain is all beta (see below).
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