Words similar to rlk
Example sentences for: rlk
How can you use “rlk” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus, although Rlk, like Itk and Btk, is activated by phosphorylation by Src family kinases and can be found in RAFTs, its requirements for this activation may be unique.
To determine the requirements for Rlk activation downstream from the TCR, we introduced constructs expressing Rlk-GFP or Rlk-GFPY420F into the Jurkat-Tag cell line.
Since these GFP fusions behaved similarly to wildtype Rlk in all known respects except for electrophoretic mobility, we used GFP fusions of mutant and wild type versions of Rlk to facilitate studies of Rlk localization and activation.
In the presence of kinase-inactive Fyn, the half-life of Rlk was not altered, suggesting that the phosphorylation of Rlk by Fyn is necessary for the decrease in half-life of Rlk (Fig.
These results suggest that Rlk can be phosphorylated on Y420 in response to TCR stimulation, supporting a role for Rlk downstream of Src kinases in signaling from the TCR, analogous to Btk's role in signaling from sIgM.