Example sentences for: riα
How can you use “riα” in a sentence? Here are some example sentences to help you improve your vocabulary:
Because RIα was observed in close association with the NMJ postsynaptic membrane [ 19 ] , we probed for D-AKAP expression and possible colocalization with this and other regulatory subunits.
We found partial overlap of the RIα label with synaptophysin, which labels presynaptic vesicles (fig.
Our interest in PKA and PKC activity in the NMJ derives from: (1) a report that RIα not only is enriched there, but also appears to be tethered to the postsynaptic membrane [ 19 ] , (2) the rich literature describing selective PKC isoform activity and functional compartmentalization in the NMJ and skeletal muscle, (3) our discoveries that D-AKAP1 and D-AKAP2 bind to and appear to colocalize with RIα, and often mitochondria [ 15 16 28 ] ; and (4) our finding that gravin binds to both PKA and PKC [ 13 ] .
in lipid metabolism [ 39 40 ] , and a possible function of USF in tuning RIα/RIIβ ratio by activating RIα transcription and inhibiting RIIβ transcription is an interesting target of further investigation.
Only recently has the subcellular distribution of PKA at neuromuscular junctions (NMJs) and the adjacent muscle been systematically studied [ 17 18 ] . Imaizumi-Scherrer and colleagues demonstrated that RIα is localized at the NMJ [ 19 ] , but whether RI associates with a D-AKAP in this region of muscle is not known.
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