Example sentences for: riα
How can you use “riα” in a sentence? Here are some example sentences to help you improve your vocabulary:
Because the antibodies to D-AKAP1 and RIα were produced in rabbit and mouse, respectively, double-labeling confocal experiments could be performed with these antibodies on the same tissue slice in order to test for colocalization.
This suggests to us that anti-D-AKAP1 may be occluding RIα bound to D-AKAP1 to the extent that anti-RIα has little access to its antigen.
Our interest in PKA and PKC activity in the NMJ derives from: (1) a report that RIα not only is enriched there, but also appears to be tethered to the postsynaptic membrane [ 19 ] , (2) the rich literature describing selective PKC isoform activity and functional compartmentalization in the NMJ and skeletal muscle, (3) our discoveries that D-AKAP1 and D-AKAP2 bind to and appear to colocalize with RIα, and often mitochondria [ 15 16 28 ] ; and (4) our finding that gravin binds to both PKA and PKC [ 13 ] .
The distribution of D-AKAP1 at the postsynaptic NMJ and the adjacent muscle is similar to that of RIα, although there is no codistribution at the presynaptic region between these two labels (fig.
In the postsynaptic region, RIα immunoreactivity showed partial overlap with the mitochondrial marker (lipoic acid); overlap with mitochondria in muscle fibers was also observed (fig.