Example sentences for: riα
How can you use “riα” in a sentence? Here are some example sentences to help you improve your vocabulary:
Only recently has the subcellular distribution of PKA at neuromuscular junctions (NMJs) and the adjacent muscle been systematically studied [ 17 18 ] . Imaizumi-Scherrer and colleagues demonstrated that RIα is localized at the NMJ [ 19 ] , but whether RI associates with a D-AKAP in this region of muscle is not known.
Furthermore, RIα was shown to bind to cytochrome c oxidase subunit Vb (a mitochondrial inner membrane protein), which faces the matrix, in a cAMP-dependent manner [ 35 ] . How RIα passes across the mitochondrial inner membrane is not known.
We found partial overlap of the RIα label with synaptophysin, which labels presynaptic vesicles (fig.
Because the antibodies to D-AKAP1 and RIα were produced in rabbit and mouse, respectively, double-labeling confocal experiments could be performed with these antibodies on the same tissue slice in order to test for colocalization.
However, a new class of AKAPs was discovered when two dual-specific AKAPs (D-AKAP1 and D-AKAP2) were cloned using a fusion protein of the RIα as the bait in a yeast two-hybrid screen [ 15 16 ] ). Therefore, the contrasted distribution pattern between RI and RII may in part be due to selective association with different compartmentalized pools of AKAPs.
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