Words similar to ribonucleoprotein
Example sentences for: ribonucleoprotein
How can you use “ribonucleoprotein” in a sentence? Here are some example sentences to help you improve your vocabulary:
This finding is not anomalous because analysis of exon sequences surrounding the total set of introns in S. cerevisiae pre-mRNA genes shows a preference for AAAG at the 5' splice site [ 31 ] . The final G in this motif has been established as significantly conserved in yeast [ 32 ] . The sequence at the proximal 5' exon region is required for interactions with the spliceosomal small nuclear ribonucleoprotein particle U1 [ 19 ] . Our data are, therefore, consistent with present understanding of yeast pre-mRNA splicing.
This ribonucleoprotein (RNP) complex is an endonuclease, which can initiate reverse splicing into an intron-less target site in a process known as retrohoming [ 3 ] . After the intron RNA reverse splices into one strand of the double-stranded DNA, the intron-encoded protein cleaves the other strand at position +9 or +10 downstream of the intron insertion site, and the generated 3' end of the second strand is used as a primer for reverse transcription of the inserted intron RNA.
Although direct evidence that autoantigen cleavage fragments produced during cell death elicit autoantibody responses is still scarce, Pollard et al . reported that immunization of B10.S mice (H-2 s) with a 19 kDa proteolytic cleavage fragment of fibrillarin (derived from nonapoptotic cell death) elicited antibodies that are comparable with human anti-fibrillarin autoantibodies and those derived from mice exposed to mercury [ 40 ] . In a study using human sera, Greidinger et al . reported that the recognition of apoptosis-derived and oxidatively modified forms of the 70 kDa subunit of U1 small nuclear ribonucleoprotein autoantigen was associated with distinct disease manifestations [ 41 ] . Furthermore, Oriss et al . demonstrated that a combination of antigen-processing cells and a fragment of DNA topoisomerase I efficiently elicited autoreactive T-cell proliferation, whereas the full-length topoisomerase I required additional stimulus of exogenous interleukin-2 [ 42 ] .
For example, Snrpn (small nuclear ribonucleoprotein N; MGI: 98347) and Snurf ( SNRPN upstream reading frame; MGI: 1891236) are expressed as bicistronic Snurf-Snrpn transcript [ 27] and both of them were associated with one single TC (TC619385) and one single DT (DT.
CMV = cytomegalovirus; EIA = enzyme immunoassay; gB = glycoprotein B; OD = optical density; RNP = ribonucleoprotein; Sm = ribonucleoproteins recognized by antibodies from a patient named Smith; U1-70 kD = component of the U1 ribonucleoproteins.
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