Words similar to ribonucleoprotein
Example sentences for: ribonucleoprotein
How can you use “ribonucleoprotein” in a sentence? Here are some example sentences to help you improve your vocabulary:
Transcription of these genes is followed by RNA-splicing that results in intron removal (for review, see [ 1 ] ). The majority of eukaryotic spliceosomal introns interrupt pre-mRNA in the nucleus and are removed by a ribonucleoprotein complex, termed the spliceosome.
Less than 10% of the patients in all groups demonstrated antibodies to SSA, SSB, dsDNA, ribonucleoprotein (RNP), and Sm.
Antibodies to CMV gB share some homology with rheumatoid factor, thus providing a theoretical relationship between CMV infection and autoimmune disease [ 12 ] . An adenovirus-CMV gB construct vaccine administered to mice induced a statistically significant increase in the production of antibodies to U1-70 kD antibody in both normal and autoimmune-prone mice [ 13 ] . Newkirk et al . recently reported an increased incidence of antibodies to Sm antigen and antibodies to ribonucleoprotein (RNP) among naturally CMV-infected individuals, as well as an increase in antibodies to U1-70 kD [ 14 ] .
Although direct evidence that autoantigen cleavage fragments produced during cell death elicit autoantibody responses is still scarce, Pollard et al . reported that immunization of B10.S mice (H-2 s) with a 19 kDa proteolytic cleavage fragment of fibrillarin (derived from nonapoptotic cell death) elicited antibodies that are comparable with human anti-fibrillarin autoantibodies and those derived from mice exposed to mercury [ 40 ] . In a study using human sera, Greidinger et al . reported that the recognition of apoptosis-derived and oxidatively modified forms of the 70 kDa subunit of U1 small nuclear ribonucleoprotein autoantigen was associated with distinct disease manifestations [ 41 ] . Furthermore, Oriss et al . demonstrated that a combination of antigen-processing cells and a fragment of DNA topoisomerase I efficiently elicited autoreactive T-cell proliferation, whereas the full-length topoisomerase I required additional stimulus of exogenous interleukin-2 [ 42 ] .
Anti-RA-33 antibodies recognize the A2 protein, an antigen found in the heterogeneous ribonucleoprotein of the splicosome [ 19].
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