Words similar to rho
Example sentences for: rho
How can you use “rho” in a sentence? Here are some example sentences to help you improve your vocabulary:
The functions of Boi1/Boi2 appear to be linked to those of Cdc42 and Rho3, which are Rho-type GTPases that are important for polarized cell growth [ 4 5 6 7 8 9 ] . Boi1 and Boi2 display two-hybrid interactions with both wild-type and mutationally activated Cdc42 but not with a mutant version of Cdc42 that is predicted to be impaired in the ability to bind nucleotide, suggesting that Boi1 and Boi2 may associate with the GTP-bound ("active") form of Cdc42 [ 1 ] . Further evidence that some function of Boi1 is linked to that of Cdc42 is that overexpression of Boi1 inhibits bud emergence and that this inhibition can be suppressed by overexpression of Cdc42 [ 1 2 ] . RHO3 can serve as a multicopy suppressor of the lethality caused by deletion of BOI1 and BOI2 [ 1 2 ] . These findings are consistent with the possibilities that Boi1 and Boi2 are targets of Cdc42 that promote cell growth in a manner that is regulated by Rho3.
The Rho family of GTPases is largely responsible for maintenance of cell shape in a variety of cell types, and this involves regulation of the actin cytoskeleton.
In this system it has been shown that Rho function is necessary for the production of actin stress fibers [ 13 ] . However, in cells that are considered highly motile and circulate through various compartments of the body (such as T lymphocytes), actin stress fibers have yet to be identified.
Through the action of farnesyl transferases and type I geranylgeranyl transferases, isoprenoids are attached to the amino acid sequence Cys-Ala-Ala-Xaa (“CAAX”) at the C-terminus of the Rho family of GTPases [20].
In static cell adhesion assays, however, Rho activity is not required to maintain constitutively high levels of adhesion to fibronectin.
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