Words similar to rhabdomyosarcoma
Example sentences for: rhabdomyosarcoma
How can you use “rhabdomyosarcoma” in a sentence? Here are some example sentences to help you improve your vocabulary:
Most cases of alveolar rhabdomyosarcoma are associated with a chromosomal translocation t(2; 13) (q35; q14), and less commonly with t(1; 13)(p36; q14) [ 6 7 8 9 ] . The t(2; 13) translocation results in fusion of a portion of the Pax3 gene to a portion of the FKHR gene, leading to formation of fusion protein Pax3-FKHR.
The p53 mutant mice tend to develop rhabdomyosarcoma [ 29 ] . P53 is a tumor suppressor regulating cell cycle control and apoptosis, and p53 is one of the many downstream targets of ATM kinase [ 25 27 ] . ATM phosphorylate p53 at Serine 15 in response to DNA damage agents [ 17 ] . It is unknown how the mutated ATM contributes to pathogenesis of rhabdomyosarcoma in the presence of the mutated p53.
The levels of ATM expression in these three rhabdomyosarcoma cell lines are not identical, and Rh30 cells seemed to express less ATM than the other two Rhabdomyosarcoma cells.
Human cell lines used in this study were the fibrosarcoma cell line HT1080; rhabdomyosarcoma cell line RD stably transfected with human α3 integrin (RD A3); lymphoblastoid T cell line Molt4, human mammary epithelial cell line MTSV 1-7; erythroleukemia K562 cells and φ nx-Eco packaging cells.
We used reverse transcription-PCR method to analyze five different rhabdomyosarcoma cell lines, RD cells (embryonal), Rh28, Rh30 (alveolar), Rh3, Rh4, and mouse normal myoblast C2C12 cells.
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