Words similar to rhabdomyosarcoma
Example sentences for: rhabdomyosarcoma
How can you use “rhabdomyosarcoma” in a sentence? Here are some example sentences to help you improve your vocabulary:
The p53 mutant mice tend to develop rhabdomyosarcoma [ 29 ] . P53 is a tumor suppressor regulating cell cycle control and apoptosis, and p53 is one of the many downstream targets of ATM kinase [ 25 27 ] . ATM phosphorylate p53 at Serine 15 in response to DNA damage agents [ 17 ] . It is unknown how the mutated ATM contributes to pathogenesis of rhabdomyosarcoma in the presence of the mutated p53.
The levels of ATM expression in these three rhabdomyosarcoma cell lines are not identical, and Rh30 cells seemed to express less ATM than the other two Rhabdomyosarcoma cells.
Both Pax3-FKHR and Pax7-FKHR were shown to possess more potent transcriptional activity than its original forms Pax3 and Pax7 [ 10 11 ] . How the chimeric fusion proteins contribute to pathogenesis of rhabdomyosarcoma remains unclear.
These patients all carried clinical histopathological diagnoses of rhabdomyosarcoma (embryonal or alveolar type), and showed immunostaining positivity for myogenin, a specific skeletal muscle marker.
In this study, we report an association of human rhabdomyosarcoma with deletion/mutation of ATM gene.