Example sentences for: rhabdomyosarcoma

How can you use “rhabdomyosarcoma” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Histopathologically rhabdomyosarcoma can be divided into two major subtypes, embryonal rhabdomyosarcoma representing about 80% of the clinical cases, and alveolar rhabdomyosarcoma representing about 20% of the total cases [ 1 2 ] . Extensive cytogenetic studies showed that the embryonal rhabdomyosarcomas are generally associated with loss of heterozygosity (LOH) for multiple closely linked loci at chromosomal 11p15.

  • Examples include RPs L7a, L37 and S14 in prostate tumors and cell lines [ 20 ] ; RPs L5, L7A, L18, S3, S6, S8, S12, S13, S28, P0 and P1 in colorectal cancers and cell lines [ 21 22 23 24 25 26 ] ; L5 in astrocytomas [ 27 ] ; L18a in squamous cell carcinoma [ 28 ] ; L19 in breast tumors that over-express erbB-2 [ 29 ] ; RPs S3A, S4, and S17 in lymphoid malignancies [ 30 ] ; L38, S4, P0, and P1 in rhabdomyosarcoma cell lines [ 31 ] ; and P0, P1, P2, L5, L9, L35, L39, S3A, S10, and S17 in liver tumors [ 32 ] . In addition, as noted above, a recent SAGE study identified targets of N-myc in a human neuroblastoma cell line [ 18 ] . Of 114 up-regulated genes detected, 66 encoded RPs with elevations ranging from 40% to 37-fold.

  • It is surprising to note that 7 of the17 (41%) rhabdomyosarcoma specimens stained negatively for the presence of ATM protein.

  • In fact, the rhabdomyosarcoma cells Rh30 is known to have p53 mutation, and is also positive for t(2; 13) chromosomal translocation [ 11 ] . Further investigations are needed to address these important questions.

  • Using the same experimental conditions, we were unable to detect α4β1 in CD98 immunoprecitates prepared from the rhabdomyosarcoma cell line RD, the lymphoblastoid cell line Molt4, or K562 cells transfected with α4 integrin (not shown).


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