Example sentences for: rhabdomyosarcoma

How can you use “rhabdomyosarcoma” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The p53 mutant mice tend to develop rhabdomyosarcoma [ 29 ] . P53 is a tumor suppressor regulating cell cycle control and apoptosis, and p53 is one of the many downstream targets of ATM kinase [ 25 27 ] . ATM phosphorylate p53 at Serine 15 in response to DNA damage agents [ 17 ] . It is unknown how the mutated ATM contributes to pathogenesis of rhabdomyosarcoma in the presence of the mutated p53.

  • The levels of ATM expression in these three rhabdomyosarcoma cell lines are not identical, and Rh30 cells seemed to express less ATM than the other two Rhabdomyosarcoma cells.

  • Both Pax3-FKHR and Pax7-FKHR were shown to possess more potent transcriptional activity than its original forms Pax3 and Pax7 [ 10 11 ] . How the chimeric fusion proteins contribute to pathogenesis of rhabdomyosarcoma remains unclear.

  • These patients all carried clinical histopathological diagnoses of rhabdomyosarcoma (embryonal or alveolar type), and showed immunostaining positivity for myogenin, a specific skeletal muscle marker.

  • In this study, we report an association of human rhabdomyosarcoma with deletion/mutation of ATM gene.


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