Example sentences for: rfz-

How can you use “rfz-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Both have been shown to elevate intracellular Ca 2+levels and to activate PKC and CamKII [ 4 5 6 ] . In addition Wnt-5a and Rfz-2 have been shown to synergize in their induction of CamKII [ 6 ] . Wnt-1/C57mg cells were also used for comparison, in an effort to identify genes preferentially regulated by Wnt-5a.

  • The list of genes shows those that are specific to Wnt-5a/Rfz-2, differential between Wnt-5a/Rfz-2 and Wnt-1, specific to Wnt-1, and common to both Wnt-1 and Wnt-5a/Rfz-2.

  • A similar level of induction was also observed with Wnt-5a/293T cells co-cultured with Rfz-2/C57mg cells (data not shown), suggesting that the induction of SL-1 is due to expression of Wnt-5a and not only to Rfz-2.

  • A recent report demonstrated that Wnt-5a and Rfz-2 can induce the nuclear localization of the transcription factor NF-AT [ 14 ] . Their results show that NF-AT is a downstream target of the Wnt/Ca 2+pathway and antagonizes the Wnt/beta-catenin pathway in Xenopus embryos.

  • Whether mesothelin and SL-1 are direct targets of Wnt-1 and Wnt-5a, respectively, and whether alterations in their expression are responsible for the observed phenotypic changes in Wnt-5a/Rfz-2/C57mg cells, has yet to be determined.


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