Words similar to rexinoids
Example sentences for: rexinoids
How can you use “rexinoids” in a sentence? Here are some example sentences to help you improve your vocabulary:
We have used several approaches to specifically examine the responsiveness of the CAR/RXR heterodimer to rexinoids.
The results described here also suggest that rexinoids may have modulatory effects on xenobiotic responses, and that such effects may differ for different CAR/RXR target genes.
At least one third of the 48 human members of the nuclear hormone receptor superfamily function as heterodimers with the Retinoid X Receptors, (RXRs, NR2B1-3) [ 1 ] . Some, but not all of these heterodimers can be directly activated by RXR agonists, called rexinoids, which include the endogenous ligand 9-cis-retinoic acid (9-cis-RA) and a number of synthetic compounds.
Direct biochemical measurements demonstrate that rexinoids can induce coactivator binding, but can also inhibit the effects of CAR agonist and inverse agonist ligands.
The disparities in these responses preclude a single, simple explanation for the effects of rexinoids on CAR/RXR heterodimers.