Words similar to rexinoids

Example sentences for: rexinoids

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Overall, we conclude that the disparate effects of rexinoids on CAR/RXR heterodimers in different contexts add significantly to the potential complexity of the effects of RXR ligands on such nuclear receptor heterodimers, and demonstrate that classifying a particular complex as permissive or non-permissive can be an oversimplification.
Initial functional results suggested that transactivation by CAR/RXR heterodimers is not affected by RXR ligands, including 9-cis-RA or synthetic rexinoids, indicating that CAR is a non-permissive RXR partner.
Overall, these results significantly increase the potential complexity of the response of RXR heterodimers to RXR ligands and suggest a potential modulatory effect of rexinoids on xenobiotic responses.
Effects of rexinoids on CAR responses to agonist and inverse agonist ligands in cells
The results described here also suggest that rexinoids may have modulatory effects on xenobiotic responses, and that such effects may differ for different CAR/RXR target genes.