Words similar to rexinoids
Example sentences for: rexinoids
How can you use “rexinoids” in a sentence? Here are some example sentences to help you improve your vocabulary:
The disparities in these responses preclude a single, simple explanation for the effects of rexinoids on CAR/RXR heterodimers.
To test the effects of rexinoids on coactivator binding in a defined biochemical system, surface plasmon resonance was used to characterize the effects of the various ligands on binding of CAR, RXR and CAR/RXR heterodimers to SRC-3 (also known as ACTR, p/CIP, RAC3, AIB1, TRAM-1), an effective coactivator for CAR and many other members of the nuclear receptor superfamily.
Overall, these results significantly increase the potential complexity of the response of RXR heterodimers to RXR ligands and suggest a potential modulatory effect of rexinoids on xenobiotic responses.
We have used several approaches to specifically examine the responsiveness of the CAR/RXR heterodimer to rexinoids.
Further characterization of potential CAR cofactors, as well as the development of sensitive and direct ligand binding assays will be required to define the molecular mechanisms that account for the diverse effects of rexinoids on CAR transactivation.