Words similar to rexinoid

Example sentences for: rexinoid

How can you use “rexinoid” in a sentence? Here are some example sentences to help you improve your vocabulary:

The rexinoid alone has no effect on transactivation of the βRARE, but strongly inhibits responses to both the agonist TCPOBOP and the inverse agonist androstanol.
To test whether the apparent allosteric effects of LG1069 on CAR transactivation vary with different response elements, the effect of the rexinoid on transactivation directed by cytochrome P450 response elements was examined.
In transient transfections, the rexinoid LG1069 shows different effects on the ability of the xenobiotic receptor to transactivate various response elements.
Recent results suggest that the C-terminal helix 12 of RXR exerts allosteric effects on RAR function [ 6 ] . However, additional studies suggest that corepressor binding to the apo-RAR component of the heterodimer blocks rexinoid induced binding of coactivators to RXR [ 7 ] . These results suggest that the mechanisms that account for the lack of responsiveness of the non-permissive complexes are complex.
The rexinoid responsive complexes are referred to as permissive and include the Peroxisome Proliferator Activated Receptor (PPAR) and the Farnesoid X Receptor (FXR) heterodimers; the Retinoic Acid Receptor (RAR), and Thyroid Hormone Receptor (TR) heterodimers are non-permissive [ 2 3 4 5 6 7 ] .