Words similar to rexinoid

Example sentences for: rexinoid

How can you use “rexinoid” in a sentence? Here are some example sentences to help you improve your vocabulary:

In this context, the rexinoid blocks activation by the agonist TCPOBOP.
The rexinoid alone has no effect on transactivation of the βRARE, but strongly inhibits responses to both the agonist TCPOBOP and the inverse agonist androstanol.
Recent results suggest that the C-terminal helix 12 of RXR exerts allosteric effects on RAR function [ 6 ] . However, additional studies suggest that corepressor binding to the apo-RAR component of the heterodimer blocks rexinoid induced binding of coactivators to RXR [ 7 ] . These results suggest that the mechanisms that account for the lack of responsiveness of the non-permissive complexes are complex.
To examine the effects of RXR ligands on CAR transactivation in a more functional context, the rexinoid LG1069 was combined with the CAR inverse agonist androstanol and the agonist TCPOBOP in a series of transient transfection studies using different response elements.
The rexinoid responsive complexes are referred to as permissive and include the Peroxisome Proliferator Activated Receptor (PPAR) and the Farnesoid X Receptor (FXR) heterodimers; the Retinoic Acid Receptor (RAR), and Thyroid Hormone Receptor (TR) heterodimers are non-permissive [ 2 3 4 5 6 7 ] .