Words similar to reversible
Example sentences for: reversible
How can you use “reversible” in a sentence? Here are some example sentences to help you improve your vocabulary:
2) Does the heat pretreatment response diminish by prolonged recovery at 37°C after heat treatment, i.e. is the heat pretreatment reversible?
The claim that such turbidity did not affect 13C-NMR measurements [ 3 5 6 ] contrasts with evidence that even small multimers can change NMR chemical shifts [ 25 26 ] . It should be noted also that, at high concentrations of B =, extensive, reversible self-association of B =can lead to apparently stable supersaturation with no separation of an insoluble phase [ 2 ] . For example, at pH 8.5 and a UCB concentration of 20 μM (63 times S), the weight-average aggregation number of UCB has been found to be 7.17 [ 18 ] , corresponding to a molecular weight of 4,195.
Cellulose acetate phthalate (CAP) is a promising microbicide candidate for prevention of infection by sexually transmitted disease (STD) pathogens, including HIV-1 [ 1 2 3 4 5 6 7 ] . CAP inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120, while leaving the site for the primary cellular receptor CD4 accessible [ 8 9 ] Soluble CD4 (sCD4) was shown to inhibit HIV-1 infection by two mechanisms: reversible blockage of virus binding to receptors, and irreversible inactivation of virus infectivity [ 10 ] . Since CAP and sCD4 bind to distinct domains on the HIV-1 envelope, it was of interest to determine whether or not these two ligands affect virus infectivity synergistically as do other combinations of anti-HIV-1 drugs and sCD4 [ 11 12 ] Binding of sCD4 leads to conformational changes in gp120 [ 13 14 15 16 17 ] . Binding of gp120 to coreceptors CXCR4 and CCR5, respectively, triggers additional conformational changes in HIV-1 envelope glycoproteins [ 18 19 ] For these reasons it was of interest to determine whether a) pretreatment of HIV-1 with sCD4 would affect subsequent binding of CAP to virus particles, and b) CAP binding to virus particles in the presence or absence of sCD4 would elicit conformational changes which could affect HIV-1 infectivity.
To test the hypothesis that transient inhibition of proteasomal activity during mouse meiosis I was associated with chromosome missegregation, mouse oocytes were exposed in vitro to the reversible proteasome inhibitor MG-132 and metaphase II (MII) oocytes were analyzed for structural and numerical chromosome aberrations.
Because the effects of ISIS 15534 treatment are not readily reversible, the washout experiments needed to distinguish between these two possibilities cannot be conducted until a specific and reversible inhibitor of PP5 is developed.
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