Example sentences for: require

How can you use “require” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Even if these findings are not confirmed after further study, one could still make a compelling argument that lipid-lowering therapy (barring contraindications) should be initiated early and universally in patients who present with an acute coronary syndrome: First, the long-term safety and effectiveness of statins for the secondary prevention of stable coronary disease is well-established [ 1 2 3 ] ; Second, as evidenced by MIRACL, these agents are safe when initiated at the time of hospitalization for an acute coronary syndrome; Third, the in-hospital initiation of lipid-lowering therapy appears to promote greater long-term utilization of these agents [ 18 19 20 21 ] . Finally, although lipid levels may be unreliable in the setting of an acute coronary syndrome (excepting total :HDL and LDL:HDL cholesterol ratios [ 22 ] ) the overwhelming majority of patients with coronary disease will ultimately require both pharmacologic and non-pharmacologic lipid-lowering interventions to attain recommended cholesterol targets [ 23 24 25 ] ; newer guidelines are even more stringent [ 26 ] . Furthermore, data from the recently presented Heart Protection Study suggest that clinical benefits may accrue independent of baseline cholesterol level [ 4 ] . Thus, to withhold lipid-lowering therapy from patients who present with an acute coronary syndrome would be to accept the status quo, and to date our efforts at cholesterol lowering in the secondary prevention setting have been dismal [ 27 28 ] .

  • ). A more promising direction is simply to require American leaders to absorb their Secret Service code names into their proper names.

  • The overwhelming majority of DOD's major acquisitions today require major leaps in capability over their predecessors or any other competing weapon systems, with little knowledge about the resources that will be required to design and manufacture the systems.

  • Pooling data in this way will require judicious and well justified statistical procedures.

  • We also recognize that the practices require customized application at individual organizations depending on factors such as existing organizational strengths and weaknesses.


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