Example sentences for: repressors

How can you use “repressors” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These ORFs have sequence similarity to a conserved hypothetical protein found in several bacterial genera and the tetR family of transcriptional repressors, respectively.

  • The MYND domain is located between the two halves of the SET domain and similar domains have been identified in a number of proteins that function as transcriptional repressors, including the ETO protein that is fused to the AML-1 transcription factor in the t(8;21) translocation in acute myeloid leukemias [ 39 ] . The MYND contains two zinc finger motifs and is a protein-protein interaction interface responsible for the recruitment of corepressors [ 39 40 41 ] .

  • Therefore, some gene-specific specialization exists among these three glucose-dependent repressors.

  • In transfected cells, subdomains of TAF II 135 can act as dominant negative repressors of CREB activity [ [ 26 27 28 ] ]. It has further been suggested that some neurodegenerative diseases may result from sequestration of TAF II 135 by expanded polyglutamine domains and consequent interference with CREB activity [ 29].

  • These hybrid molecules activate transcription [ 9 31 ] . It may be possible to produce small-molecule activators (or repressors) that bind DNA specifically, but also activate transcription of adjacent genes through a non-peptidic, more drug-like moiety.


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