Words similar to repressor
Example sentences for: repressor
How can you use “repressor” in a sentence? Here are some example sentences to help you improve your vocabulary:
These previous studies have revealed that Topo I can act as either an activator or a repressor, depending on the promoter and the presence of other transcription factors [ 29].
In normal erythroid cells it acts as a repressor of the β-globin gene [ 22 23 ] . However, BP1 was also expressed in 47% of the adult and 81% of the pediatric acute myeloid leukemia patients we examined, and its overexpression increased the leukemogenic potential of K562 cells in vitro [ 11 ] . Molecular analysis revealed that BP1 expression is required for the survival of K562 leukemia cells, suggesting that BP1 might be part of an anti-apoptotic pathway (Davenport GJ, Fu S, Haga SB, Do K, Stevenson H, Pinzone J, Chase MB, Berg PE, unpublished data).
As the lac repressor variant that we used binds to the operator sites as dimers, we should be able to inhibit its binding to the LacOs of the tagged loci by adding IPTG [ 27].
The progress of the selection was monitored in two ways: first, the autogene constructs were under the control of the lac repressor, and we had previously noted that complete depression of the wild-type autogene by IPTG led to cell death.
This altered configuration may prevent the mutant receptor from releasing repressor proteins or recruiting coactivators in the presence of ligand.