Example sentences for: release

How can you use “release” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • "Most trout fishermen practice 'catch and release,' although it is true that some still catch and eat.

  • GAO reserves the right to release any product that has been issued but is under restriction if it is leaked or otherwise made publicly available.

  • Surprisingly, cdc5-1 cells grown at 25°C could exit mitosis despite persistent nucleolar localization of Cdc14, which may have been due to release of a small fraction of Cdc14 that was nevertheless sufficient to drive exit from mitosis in these cells.

  • In agreement with previous studies, the Tie1 receptor was detected on vascular endothelial cells [ 4 25 ] and recently on synovial lining cells [ 26 ] . It has been shown that tumor necrosis factor-α and VEGF activate membrane-associated metalloproteinases that release soluble Tie1 from the cell surface of endothelial cells and thereby decrease membrane-bound Tie1 expression [ 27 ] . The upregulation of Tie1 mRNA and protein expression in RA is not consistent with these findings and this may be due to the fact that the inflammatory milieu in RA synovial tissue is far more complex than the in vitro system.

  • First, net1(7m) and net1(19m') mutants exerted a modest effect on release of Cdc14 from the nucleolus, in that ~40% of cells with long mitotic spindles retained focal localization of Cdc14 and that both net1 phospho-site mutants displayed a modest defect in 'Cdc14 early anaphase release' (FEAR; [ 26 ] ). Second, net1(19m') showed a synthetic growth defect when combined with dbf2-1 or the msd2-1 allele of CDC5 . Third, phosphorylation site mapping of Net1 purified from arrested cdc14-1 cells (WS and SC, unpublished data) revealed that at least one (S231) of the five in vivo phosphorylation sites in the first 341 amino acids was directly phosphorylated by Cdc5 in vitro . Nevertheless, because expression of neither Net1(7m) nor Net1(19m') had a major impact on exit from mitosis, any direct effect of Cdc5 on Net1 appears to be minor, and the requirement for Cdc5 in the release of Cdc14 might arise principally from phosphorylation of other release-promoting proteins.


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