Words similar to release
Example sentences for: release
How can you use “release” in a sentence? Here are some example sentences to help you improve your vocabulary:
The abnormal release of growth hormone, cortisol, and epinephrine leads to impaired insulin secretion, and causes insulin resistance and hyperglycemia due to increased glycogenolysis, gluconeogenesis, and decreased glucose disposal.
It is well known that acute lung infection and septic shock may impair hypoxic pulmonary vasoconstriction through the massive release from activated endothelium of vasodilating mediators such as prostaglandins and endogenous NO, and hence result in disproportionately high shunting and hypoxemia [ 26, 27, 28, 29, 30, 31, 32].
Recent work has shown that the Bcl-2 family regulates mitochondrial homeostasis during apoptosis [ 1 ] . Pro-apoptotic members, including Bax, Bak, Bid, and Bim, promote the release of death-inducing proteins, such as cytochrome c [ 2 3 ] , smac [ 4 ] , and endonuclease G [ 5 ] , from mitochondria while anti-apoptotic members, such as Bcl-2 and Bcl-X L , inhibit this release.
The selective suppression of Th1 cell activity is believed to be due to IL-10 inhibition of IL-12, a differentiation factor for Th1 cells [ 11 12 ] . The release of reactive oxygen and nitrogen intermediates by macrophages is also suppressed by IL-10 [ 13 14 ] . In addition, IL-10 stimulates the production of cytokine inhibitors such as IL-1 receptor antagonist [ 15 ] . In patients with rheumatoid arthritis, IL-10 is produced by synovial membrane cells and is found at high levels in the synovial fluid [ 16 17 ] . It has been shown that suppression of IL-10 production by synovial cells is associated with increased levels of IL-1 and TNF-α, suggesting that IL-10 plays a suppressive role in rheumatoid arthritis joints [ 16 ] . It was also observed that IL-10 directly stimulated proteoglycan synthesis and reversed the cartilage degradation induced by activated mononuclear cells [ 18 ] . These immunosuppressive activities indicate that IL-10 is a potential therapeutic approach for autoimmune diseases.
We first subdivided Release 3 of the D. melanogaster genome [ 36 ] into 1,287 contigs of 100,500 nucleotides each, with 500 nucleotides of overlap at either end.
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