Words similar to reconstitution
Example sentences for: reconstitution
How can you use “reconstitution” in a sentence? Here are some example sentences to help you improve your vocabulary:
Biochemical reconstitution studies using purified recombinant actin in vitro and studies in RSV-infected cells ( ex vivo ) demonstrated that actin functions as a viral transcription factor in both monomeric (G) and filamentous (F) forms, whereas the filamentous form appeared to be particularly important for viral morphogenesis [ 10 ] . Subsequent studies showed that at saturating actin concentration, profilin stimulated viral transcription even further, whereas profilin by itself had no transcriptional activity in the absence of actin [ 11 ] . These results suggested that the interaction of profilin with actin may be important for optimal activity of the RSV transcriptase.
Several groups developed a more direct approach for determining occupancy by analyzing effects on the composition of the final complex, after in vitro reconstitution, when amino acid residues in LHCPs were replaced with substitutes that are unable to serve as a ligand.
Less strong Lewis bases are the charge-compensated Glu in an ion-pair with Arg, the amide group of Gln and Asn, and finally the carbonyl of the peptide backbone as the weakest [ 29 ] . The importance of the ligand was demonstrated by substitution of His with the weaker Lewis base Asn in the apoprotein of the bacterial light-harvesting complex LH1, which eliminated assembly of the complex in vivo and reconstitution in vitro [ 30 ] . Formation of a stable coordination bond with a weaker Lewis base is expected to require a stronger Lewis acid.
was observed, confirming the absence of significant differences in the retention of baseline immune reconstitution correlates between arms.
Taken together, while our data show no clinically significant benefit for repeated TIs of less than 1.5 mo in patients with CD4 counts greater than 400 on therapy with regard to viral control as defined by time to rebound, secondary outcomes document no significant difference in levels of retention of immune reconstitution between arms and no increased incidence of virological failure as a consequence of TIs.
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