Words similar to receptors
Example sentences for: receptors
How can you use “receptors” in a sentence? Here are some example sentences to help you improve your vocabulary:
Several lines of evidence indicate that NF-κB is constitutively activated in cancer cells, suggesting that it plays an important role in tumorigenesis [ 30 ] . Activated glucocorticoid receptors have been shown to repress NF-κB-mediated gene expression [ 31 ] , and to cause a significant reduction in nuclear levels of p65 protein, a subunit of NF-κB [ 31 ] . A variety of mitogens, cytokines, and reactive oxygen intermediates have been shown to rapidly cause the translocation of NF-κB to the nucleus [ 30 31 32 ] , and the ability of dexamethasone to interfere with this translocation is blocked by prior treatment with the glucocorticoid antagonist RU 486 [ 30 ] . Based on these findings, it is plausible to speculate that exposure to RU 486 may interfere with the function of endogenous glucocorticoids as regulators of cell cycle, allowing the initiation and progression of malignant transformation of liver cells.
Dani points out that the body's own agent, acetylcholine, acts over milliseconds to activate nicotinic receptors, whereas nicotine itself stimulates these receptors for hours.
Interactions of chemokine and chemokine receptors might therefore be important for the accumulation of the T cells in the RA synovium.
Upon ligand binding, the SHR undergoes conformational changes that involve releas e from the repressor proteins, and translocation to the nucleus where it can bind to specific hormone responsive sequences in the DNA of genes regulated by steroid hormones [ 1 2 ] . The mechanism by which SHRs affect the rate of RNA polymerase II-directed transcription likely involves the interaction of receptors with components of the transcription preinitialization complex.
Thus these ligands can be useful in clinical applications where activation of δ opioid receptors needs to be combined with a weak action or an antagonistic action at μ opioid receptors.
Loading...