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Example sentences for: rdta
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Expression of β-actin is increased in the retinal synaptic membrane fraction isolated from the rdta transgenic mouse
Unless otherwise stated, six micrograms of SPM protein, which is within the linear range of the standard curves (data not shown), was chosen for the comparative study between the rdta and their littermate mice.
To test this notion, the SPM proteins isolated from the retinae of the rdta and their littermate controls mice were back-phosphorylated in the presence of Ca 2+/calmodulin and γ- 32P-ATP (Figure 4A).
These data indicate that GluR1 phosphorylation in vivo was enhanced in the rdta retinae relative to their littermate controls.
Experimentally induced changes in β-actin levels associated with forebrain synapses have been reported recently [ 35], and the increases observed here are most likely due to changes in the cytoskeletal structure of synapses in the retinae of the rdta mice.
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