Example sentences for: rcca
How can you use “rcca” in a sentence? Here are some example sentences to help you improve your vocabulary:
Renal cell carcinoma (RCCa) samples were collected from patients undergoing radical nephrectomy at the University of Michigan Medical Center.
In order to understand the molecular differences between Chr and CC RCCa on a broader scale, we developed a gene categorization system ("Functional Taxonomy," see Methods) in which genes were hierarchically grouped according to the cellular function of their protein products.
Pathology reports on these samples revealed that these were not RCCa samples but instead patient 20 was a papillary urothelial carcinoma and the sample from patient 18 was not a carcinoma but a benign metanephric adenoma.
The genes CA 9 ( carbonic anhydrase IX ), CCND1 ( cyclin D1 ), CDH2 ( N-Cadherin ), EGFR ( epidermal growth factor receptor ) and TGFA ( tranforming growth factor alpha ) all showed increases in CC expression that matched the literature and had p-values ≤ 0.0061 [ 11 12 13 14 15 ] . The observed decrease in CDH1 ( E-cadherin ) in CC (p-value = 0.0045) also matched previously published reports, as did the decrease in VIM ( vimentin ) expression in Chr RCCa [ 13 16 ] . VIM was also found to be increased in CC with a p-value = 0.0045, which was consistent with the literature.
The prevalence of the scattered T cells within the CC tumors was somewhat surprising, but entirely consistent with the biology of response to a treatment for RCCa, interleukin 2 (IL-2), since IL-2 activates lymphocytes against the tumor [ 23 ] .
Loading...