Example sentences for: rapamycin

How can you use “rapamycin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We also treated cultured human fetal lung explants with wortmannin, rapamycin or PD98059 in the presence or absence of insulin.

  • Thus there is interest in using this class of inhibitors for chemotherapeutic treatment of cancer and several phase I trials have been carried out [ 22 ] . Treatment of mammalian cells with rapamycin leads to dephosphorylation and activation of 4EBP, which in turn binds to and inhibits eIF4E.

  • 2shows that wortmannin (100 nM) and rapamycin (50 nM) both abolished the insulin-mediated inhibition of SP-A gene expression.

  • ANOVA = analysis of variance; Erk= extracellular signal-regulated kinase; IC 50 = half-maximal inhibition; IRS = insulin receptor substrate; LDH = lactate dehydrogenase; MAPK = mitogen-activated protein kinase; MEK = MAPK/extracellular signal-regulated kinase kinase; mTOR = mammalian target of rapamycin; PBS = phosphate-buffered saline; PI 3-kinase = phosphatidylinositol 3-kinase; RDS = respiratory distress syndrome; SD = standard deviation of the mean; SE = standard error of the mean; SP = surfactant protein; TPA = 12-

  • For example, this has been carried out with MAP kinase deletion mutants after pheromone treatment [ 10], deletions of effectors of the Tor proteins after rapamycin treatment [ 11], and lexA deletions after UV irradiation [ 24].


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