Words similar to rapamycin
Example sentences for: rapamycin
How can you use “rapamycin” in a sentence? Here are some example sentences to help you improve your vocabulary:
Rapamycin completely abolished the phosphorylation of Thr389 in p70 S6 kinase in insulin-treated cells and also abolished the basal phosphorylation of p70 S6 kinase in control cells, at both time points examined (Fig.
H441 cells resemble bronchiolar epithelial Clara cells in phenotype and produce both SP-A and SP-B mRNA and protein [ 14 ] . The hormonal regulation of SP-A and SP-B gene expression in H441 cells is similar to that observed in differentiated type II cells in human fetal lung explants [ 6 7 15 16 ] . We treated H441 cells with the four inhibitors of signal transduction: wortmannin, LY294002, rapamycin and PD98059, to elucidate which signaling pathways are activated when insulin inhibits SP-A gene expression.
Clinical trials using the rapamycin analog CCI-779 show promise for this strategy [ 22 ] . Rapamycin and its synthetic analogs block mTOR kinase activity leading to dephosphorylation of 4EBP and other mTOR substrates.
Effect of concomitant tacrolimus and rapamycin therapy on lymphocyte proliferation
In addition, and somewhat ironically, the most commonly used agents (like steroids, calcineurin inhibitors, and rapamycin) are also known to impair normal islet function and/or insulin action.
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