Words similar to rapamycin

Example sentences for: rapamycin

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In addition, and somewhat ironically, the most commonly used agents (like steroids, calcineurin inhibitors, and rapamycin) are also known to impair normal islet function and/or insulin action.
Rapamycin completely abolished the phosphorylation of Thr389 in p70 S6 kinase in insulin-treated cells and also abolished the basal phosphorylation of p70 S6 kinase in control cells, at both time points examined (Fig.
Rapamycin inhibits activation of p70 S6 kinase, a downstream effector in the PI 3-kinase signaling pathway [ 13 ] . Rapamycin forms a complex with FK506-binding protein 12 and this complex blocks the kinase activity of mTOR (mammalian target of rapamycin), a kinase upstream of p70 S6 kinase [ 20 ] . The IC 50 for p70 S6 kinase inhibition by rapamycin is ~0.
The small molecule rapamycin has been transcriptionally profiled by three research groups in four separate studies [ 4, 11, 21, 22].
Wortmannin, LY294002, rapamycin and PD98059 were reconstituted in dimethyl sulphoxide as 1 mM, 50 mM, 50 μM and 10 mM stock solutions, respectively, and stored at -80°C in aliquots.