Example sentences for: rapamycin

How can you use “rapamycin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The data presented here indicate that direct inhibition of eIF4E may be more effective and a more specific means of targeting tumor cells than treatment with rapamycin.

  • Clinical trials using the rapamycin analog CCI-779 show promise for this strategy [ 22 ] . Rapamycin and its synthetic analogs block mTOR kinase activity leading to dephosphorylation of 4EBP and other mTOR substrates.

  • If rapamycin and its analogs are to be developed as useful antitumor agents, it will be important to determine how p27 Kip1levels affect responsiveness to these compounds.

  • We also treated cultured human fetal lung explants with wortmannin, rapamycin or PD98059 in the presence or absence of insulin.

  • 4EBP phosphorylation is thought to be mediated by mammalian target of rapamycin (mTOR) in mitogen stimulated cells [ 9 10 11 ] .


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