Example sentences for: rankl-mediated

How can you use “rankl-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To characterize this RANKL-mediated resistance to IFN-γ, we performed a series of dose-response and time course experiments.

  • With respect to osteoclast formation, IFN-γ is known to potently inhibit RANKL-mediated osteoclastogenesis in both spleen-derived macrophage cultures and bone marrow coculture systems [ 19 20 21 ] . It has also been demonstrated that mice defective in IFN-γ signaling have a more rapid onset of arthritis and bone resorption compared with wild-type mice, suggesting a protective role of IFN-γ in early arthritis [ 21 22 ] .


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