Words similar to rankl
Example sentences for: rankl
How can you use “rankl” in a sentence? Here are some example sentences to help you improve your vocabulary:
In osteoclast precursors, RANKL induced increasing TRAP expression until virtually 100% of mononuclear cells were highly TRAP-positive.
These results imply a model for arthritic joints in which macrophage precursors entering an inflamed joint are exposed to RANKL and are subsequently rendered resistant to the anti-osteoclastogenic effects of IFN-γ expressed by activated T cells in the synovium.
Bone-resident macrophages pre-exposed to RANKL in the stromal environment may be resistant to the immunoregulatory effects of IFN-γ, and may thus be better suited for bone-remodeling tasks.
Pretreatment with RANKL inhibited IFN-γ-induced NO production in a dose-dependent and time-dependent manner (Fig.
These data may help explain the contradictory findings regarding the effects of IFN-γ as an inhibitor of osteoclastogenesis, and also suggest a model of erosive disease in the presence of IFN-γ whereby osteoclast precursors are exposed to RANKL before they enter the IFN-γ-rich environment.