Example sentences for: rankl

How can you use “rankl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In contrast, peripheral blood macrophages not exposed to RANKL may be more responsive to the macrophage-activating immunoregulatory effects of IFN-γ, and may thus be better suited for antimicrobial activities.

  • As described by Hofbauer et al [ 24], the quantity of bone resorbed depends on the balance between expression of RANKL and of its inhibitor, osteoprotegerin (OPG).

  • A dose of 200 ng/ml GST-RANKL had equivalent bioactivity to 100 ng/ml eukaryotically expressed human RANKL protein (donated by Immunex).

  • These results imply a model for arthritic joints in which macrophage precursors entering an inflamed joint are exposed to RANKL and are subsequently rendered resistant to the anti-osteoclastogenic effects of IFN-γ expressed by activated T cells in the synovium.

  • We demonstrate that pre-osteoclasts stimulated with RANKL for 2 days are rendered resistant to the IFN-γ induced inhibition of osteoclastogenesis, NO production, and upregulation of CD11b and RANK surface expression.


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