Example sentences for: rankl

How can you use “rankl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • RANKL pretreatment inhibits IFN-γ-induced macrophage activation

  • Hofbauer et al suggest that the stimulation of the pool of M-CSF precursors to committed osteoclastogenesis by RANKL may be one of the central pathophysiologic pathways involved in increasing the number of osteoclasts in osteoporosis.

  • These cells produce macrophage colony-stimulating factor (M-CSF) and the receptor for activation of nuclear factor kappa b (NF- k B) (RANK) ligand (RANKL).

  • The duration of RANKL pretreatment was also important; the longer the pretreatment phase, the greater the resistance to IFN-γ (Fig.

  • These data support the hypothesis that sensitivity to IFN-γ decreases with increasing osteoclast differentiation and that the mechanism by which RANKL and IFN-γ reciprocally inhibit each other in pre-osteoclasts is mediating the irreversible commitment into the osteoclast or activated macrophage lineages.


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