Example sentences for: rankl

How can you use “rankl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the present study we analyzed cytokine (IL-2, IL-4, IL-6, IL-10, IL-13, IFN-γ , TNF-α , and LT-α ), activation marker (CD154 [CD40 ligand] and TRANCE - also called receptor activator of nuclear factor κ B ligand [RANKL] or osteoclast differentiation factor [ODF]), and chemokine receptor expression by individual CD4 +memory T cells isolated from rheumatoid synovium and blood.

  • In the case of circulating or peripheral macrophages that have not encountered osteoclastogenic quantities of RANKL, IFN-γ rapidly induces macrophage activation and subsequent NO production, recruiting these cells for immune responses.

  • The molecular mechanisms underlying the contrasting effects of IFN-γ and RANKL remain elusive.

  • It is possible that RANKL and IFN-γ expression by activated T cells may be a major mechanism by which T cells control the fate of osteoclasts, and that relative expression of both molecules will dictate whether osteoclasts are induced or inhibited.

  • BSA = bovine serum albumin; DMEM = Dulbecco's modified Eagle's medium; FACS = fluorescence-activated cell sorting; Fc = crystallizable fragment; FITC = fluorescein isothiocyanate; IFN = interferon; IL = interleukin; MHC = major histocompatibility complex; NF = nuclear factor; NO = nitric oxide; RANK = receptor-activator of NFκB; RANKL = receptor-activator of NFκB ligand; Th = T helper cells; TRAP = tartrate-resistant acid phosphatase.


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