Words similar to rankl
Example sentences for: rankl
How can you use “rankl” in a sentence? Here are some example sentences to help you improve your vocabulary:
Future studies in this area are needed to better understand how T cells producing both IFN-γ and RANKL mediate immunity and bone resorption, and to better elucidate their role in the pathogenesis of diseases such as osteomyelitis and erosive arthritis.
Bone-resident macrophages pre-exposed to RANKL in the stromal environment may be resistant to the immunoregulatory effects of IFN-γ, and may thus be better suited for bone-remodeling tasks.
GST-RANKL was purified as described previously [ 32 ] . Briefly, a fragment of murine RANKL cDNA was cloned inframe into the pGEX-4T vector (Amersham Pharmacia, Piscataway, USA) and expressed in BL21 bacteria (Amersham Pharmacia) induced with 0.1 mM IPTG (Gibco) for 5 hours at 30°C.
RANKL pretreatment inhibits IFN-γ-induced macrophage activation
Human RANKL was a gift from Immunex (Seattle, USA) and was used to verify the efficiency of GST-RANKL protein as verified by splenic osteoclast induction.
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