Example sentences for: r-s

How can you use “r-s” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Lindsey Graham, R-S.C.

  • In the past, these compounds have been widely used as specific p38 inhibitors [ 12 ] and their inhibitory action has been well documented [ 13 14 15 ] . However, recent results show that, in a comparable concentration range they inhibit the serine/threonine kinase activity of TGFβ type I receptor preventing phosphorylation of R-Smads [ 16 17 18 ] .

  • TGFβ signals through a heteromeric receptor complex of type II and type I receptor serine-threonine kinases, which activates the downstream Smad signal transduction pathway [ 7 ] . After TGFβ binding to the receptor complex, the TGFβ type II receptor kinase phosphorylates TGFβ type I receptor which inititates the downstream response by phosphorylating receptor-regulated Smads (R-Smads), such as Smad2 and Smad3.

  • By forming a multimeric complex with the Co-Smad Smad4, activated R-Smads translocate to the nucleus and induce transcriptional modulation of target genes [ 8 ] .

  • Strom Thurmond, R-S.C.


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