Example sentences for: pyrimidines

How can you use “pyrimidines” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Because of high rates of non-integer alleles, STRPs with purines on one strand and pyrimidines on the other (eg AAGG) were avoided even though they are reasonably abundant and often especially informative [ 13 ] .

  • For example, 2'-O-methyl ribonucleotides and 5-(1-propynyl)pyrimidines have been chemically incorporated into oligonucleotides which were used to detect telomeric repeat sequences in fluorescence in situ hybridization (FISH) assays [ 19 ] . Furthermore, chimeric primers containing deoxynucleotides and 2'-O-methyl ribonucleotides have been used to eliminate artifacts, produced by exponential amplification of minor side-products, in cycle sequencing [ 20 ] .

  • The fact that DAP was able to increase hybridization intensities while MeC and MeU decreased hybridization intensities (Figures 2Dand 2E) is interesting in light of the fact that DAP is a purine incorporated into an RNA strand while MeC and MeU are pyrimidines incorporated into an RNA strand.

  • Enhanced specificity against mismatches has also been observed by other groups when DAP is incorporated into PNA oligomers [ 13 ] and after C5-(1-propynyl)ation of pyrimidines in DNA-RNA duplexes [ 33 ] .


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