Example sentences for: pyrimidine

How can you use “pyrimidine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Model building is a way of bringing into the picture previously determined bond distances and bond angles of components such as the purine and pyrimidine bases and the sugars that are unavailable from the fiber diagram.

  • This resulted in inhibition of parasite growth, consistent with the role of DHODH in pyrimidine biosynthesis, essential for parasite DNA replication.

  • Modified ribo- and deoxyribonucleoside analogs have been used in a variety of applications [ 12 13 14 ] , but their use has been limited in the field of microarrays [ 23 ] . We demonstrate that 2-aminoadenosine or 2,6-diaminopurine (DAP), an analog of adenosine, significantly increases signal intensity for a wide range of probe sequences, whereas C-5 methylated pyrimidine analogs of cytosine and uridine decreased signal intensities across the entire range of probe sequences on our platform (Figure 2).

  • Thymidylate synthase is a central enzyme of pyrimidine metabolism that catalyzes the formation of deoxythymidine monophosphate (dTMP) from deoxyuridine monophosphate (dUMP) by transfer of a methyl group to its pyrimidine ring.

  • In contrast, both of the modified pyrimidine triphosphates (MeC and MeU) tested resulted in a decrease in overall signal intensities for nearly all of the probes tested when compared against unmodified control samples (Figures 2D& 2E).


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