Example sentences for: pyrimidine

How can you use “pyrimidine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The Src inhibitor, 4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo [3,4-d]pyrimidine (PP1), was purchased from Calbiochem (La Jolla, CA).

  • Modified ribo- and deoxyribonucleoside analogs have been used in a variety of applications [ 12 13 14 ] , but their use has been limited in the field of microarrays [ 23 ] . We demonstrate that 2-aminoadenosine or 2,6-diaminopurine (DAP), an analog of adenosine, significantly increases signal intensity for a wide range of probe sequences, whereas C-5 methylated pyrimidine analogs of cytosine and uridine decreased signal intensities across the entire range of probe sequences on our platform (Figure 2).

  • In contrast, both of the modified pyrimidine triphosphates (MeC and MeU) tested resulted in a decrease in overall signal intensities for nearly all of the probes tested when compared against unmodified control samples (Figures 2D& 2E).

  • Naturally occurring analogs of purine and pyrimidine bases have been examined extensively for their ability to increase the thermodynamic stability of DNA:DNA and DNA:RNA duplexes [ 11 12 13 14 15 ] . Among these are 2-aminoadenine also known as diaminopurine (DAP), which is found in S-2L cyanophage DNA [ 16 ] , 5-methyl uracil (MeU), and 5-methyl cytidine (MeC).

  • The RADD plot will superficially resemble random walks obtained by integrating counts of purine minus pyrimidine bases.


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