Words similar to ptr
Example sentences for: ptr
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Primarily examined through the use of G-banding cytogenetic techniques, the human and common chimpanzee karyotypes differ by only 10 euchromatic rearrangements: a telomere fusion between PTR chromosomes 12 and 13, resulting in HSA chromosome 2, and 9 pericentric inversions (HSA 1, 4, 5, 9, 12, 15, 16, 17, 18) [ 1 2 ] . The predominance of pericentric inversions between chimps and humans highlights their potential importance in the divergence of human from non-human primate species, and provides an opportunity to investigate the mechanism facilitating these rearrangements.
Interestingly, all of the clones which produced the dual FISH signals in PTR were confined to a 600 kb segment of this interval.
In addition, several probes that yielded dual signals flanking the PTR centromere also produced a signal in the region orthologous to HSA 15q22-24 (Figure 3).
On the basis of the appearance of dual FISH signals on PTR XVp and XVq, the general location of the pericentric inversion breakpoint was identified with probe RP11-40J8 (Figures 1, 3).
In addition, FISH results with probe RP11-30N16, which contains the intact donor CHRNA7 locus, did not produce dual FISH signals on PTR XVp and XVq, further demonstrating this sequence is not involved in the evolutionary rearrangement.