Words similar to ptp
Example sentences for: ptp
How can you use “ptp” in a sentence? Here are some example sentences to help you improve your vocabulary:
We speak a private language--The Big Dance, PTP, zone press, subregionals--and you don't.
On the basis of sequence homo logy and similarity of three-dimensional structures, phosphoprotein phosphatases (PPases) have been classified into three families designated PPP, PPM, and PTP [reviewed in [ 1 2 3 ] . The PPP and PPM families are comprised of phosphoserine- and phosphothreonine-specific enzymes whereas the PTP family consists of phosphotyrosine-specific and dual-specificity enzymes [ 4 ] . The major members of the PPP family are PP1, PP2A, and PP2B (calcineurin) class of phosphatases.
The dephosphorylation of phosphoproteins is universally catalyzed by protein phosphatases that are classified into two major functional groups, protein tyrosine phosphatase (PTP) and protein serine/threonine phosphatase (PP) although enzymes with various degrees of dual-specificity are also encountered [ 1 2 3 4 5 ] . The majority of Ser/Thr phosphatases belong to three classical groups, namely PP1, PP2A, and PP2B (calcineurin), and possess similar primary structures in their catalytic cores [ 2 3 6 ] . PP1, in particular, exhibits an extremely high degree of sequence conservation through evolution, and its orthologs and isoforms are found in all eukaryotic cells [ 6 7 ] . In various organisms, PP1 regulates such diverse cellular processes as cell cycle progression, protein synthesis, carbohydrate metabolism, transcription, and neuronal signaling [ 3 7 ] , underscoring its profound importance in biology.
In addition, the SH3 domain of Cas mediates an interaction with FAK, C3G, CMS, and the zinc finger containing protein CIZ, while nephrocystin interacts with Cas via its SH3 domain and proline rich sequences in Cas [ 24 25 26 27 28 29 30 ] . The SH3 domain of Cas can also interact with the tyrosine phosphatase PTP1B, and expression of PTP1B in transformed cells reverts the phenotype, in part by dephosphorylating Cas [ 31 32 ] .
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