Words similar to prpp

Example sentences for: prpp

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MTX-induced enhancement of 5-phosphoribosyl-1-pyrophosphate (PRPP) pools with subsequent increased synthesis of 5-FU nucleotides and incorporation of 5-fluoriuridine - 5'-triphosphate (FUTP) into RNA has been proposed as the basis for this biochemical modulation.
It is also noteworthy that only C. psittaci has PRPP synthase, which is needed for provision of PRPP (TrpB step).
Starvation for host-derived L-tryptophan, which is initiated by induction of indoleamine dioxygenase by IFN-γ, undoubtedly triggers derepression of the entire tryptophan operon, including the genes encoding PRPP synthase and kynureninase.
The import of ATP (substrate for PRPP synthase) from the host is also probably needed, and the presence of ATP translocases in chlamydial genomes has been documented [ 1, 2, 3].
PRPP input is required for the TrpB-catalyzed step, and thus it was necessary for C. psittaci to recruit PRPP synthase ( kprS ) to the operon.