Words similar to provirus
Example sentences for: provirus
How can you use “provirus” in a sentence? Here are some example sentences to help you improve your vocabulary:
To test whether the 1B4 provirus disrupts expression of the hnRNP A2/B1 gene, RNA from wild-type mice and mice homozygous for the 1B4 provirus were analyzed by Northern blot hybridization, using hnRNP A2/B1 cDNA probes derived from sequences upstream and downstream of the integration site.
Further analysis revealed that the provirus integrated into an intron of murine homologue of the human hnRNP A2/B1 gene.
However, in approximately half of the targeted genes we have analysed [ 21 ] , the provirus has inserted into introns.
Since poly(A) sites are not usually recognised when located in introns [ 38 39 40 ] , U3 gene traps were expected to select for clones in which the provirus had inserted into exons of transcriptionally active genes.
Continued expression of hnRNP A2/B1 transcripts suggests that use of the viral poly(A) sites is less efficient than removal of the intron in which the provirus resides.
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