Words similar to provirus

Example sentences for: provirus

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The 1B4 cell line was isolated by infecting D3 ES cells with the U3Neo gene trap retrovirus and selecting for G418 resistant clones [ 29 ] . 1B4 cells contain a single, intact provirus as assessed by Southern blot hybridization (data not shown).
The 3' hnRNP A2/B1 cDNA probe hybridized to a 18 kB EcoR1 fragment corresponding to the wild type gene and to a 22 kB fragment in DNA from mice containing the 1B4 provirus (data not shown).
The flanking DNA isolated by inverse PCR extended to a HinfI site 226 nucleotides upstream and downstream of the provirus (Figure 2).
Sequences derived from hnRNPA2/B1 sequences downstream of the site of integration also hybridized to the 1.8 kb transcript in both wild type and 1B4 homozygous mice indicating that transcription of full-length hnRNP A2/B1 transcripts is not completely disrupted by the 1B4 provirus.
Provirus integration does not disrupt expression of the hnRNP A2/B1 gene