Words similar to provirus
Example sentences for: provirus
How can you use “provirus” in a sentence? Here are some example sentences to help you improve your vocabulary:
The region of the provirus LTR containing the 5' poly(A) site was amplified by PCR from genomic DNA isolated from 1B4 homozygous mice.
adjacent to the 1B4 provirus were isolated by inverse polymerase chain reaction (PCR) as reported elsewhere [ 29 ] . This flanking sequence was used as a probe to genotype mutant mice and cells by Southern blot hybridization and was also used to isolate cDNA clones encoding the murine hnRNP A2/B1 protein from a PCC3 embryonal carcinoma cell cDNA library.
MEF isolated from embryos homozygous for the 1B4 provirus showed no obvious differences from those isolated from heterozygotes or wild type embryos.
Since poly(A) sites are not usually recognised when located in introns [ 38 39 40 ] , U3 gene traps were expected to select for clones in which the provirus had inserted into exons of transcriptionally active genes.
However, in approximately half of the targeted genes we have analysed [ 21 ] , the provirus has inserted into introns.