Words similar to proviral
Example sentences for: proviral
How can you use “proviral” in a sentence? Here are some example sentences to help you improve your vocabulary:
As to HIV, how can we use our knowledge of P-TEFb to slow down viral replication and/or to eliminate the state of proviral latency in the host?
Infection of cultured podocytes with replication incompetent HIV-1 demonstrated that HIV-1 gene expression leads to the proliferation and dedifferentiation of the infected podocytes [ 6 7 8 ] , recapitulating the phenotypes observed in HIVAN specimens [ 9 10 ] . Similarly, renal expression of replication incompetent HIV-1 proviral transgenes in mice and rats produces a proliferative renal lesion that is indistiguisable both histopathologically and clinically from human HIVAN [ 11 12 13 14 ] . These observations raise the possibility that HIV-1 gene products may interact with mitogenic pathways in infected renal epithelium to cause aberrant cell-cycle engagement.
ACH2 cell lines has a single copy of LAI strain proviral sequence.
Data on log 10 proviral load were available from 38 of 46 HTLV-I subjects (mean = -2.
First, our viral backbone is a modified MoMLV vector that incorporates genetic elements (myeloproliferative sarcoma virus long-terminal repeats and B2 mutation) associated with resistance to transcriptional silencing following proviral integration in primary cells [ 7 8 ] . While we did not perform a detailed comparison of EGFP expression in FLS using the modified and unmodified vector backbones, preliminary experiments suggested that the modified vector was superior (J Yang, unpublished observations).