Example sentences for: prophase

How can you use “prophase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Separase is needed for inactivating cohesions and enabling sister chromatid separation [ 35 36 37 ] in both fission yeast [ 38 ] and mammalian cells [ 39 ] . Although differences have been reported among species [ 40 ] and cell types [ 41 ] , it appears that the majority of cohesion is removed from mammalian chromosomes during prophase and prometaphase; whereas, a lesser amount remains at kinetochores until anaphase onset.

  • Critical windows of activity in the sheep include: somatic ovarian tissue differentiation (from the gonadal ridges of the mesonephros) and growth (up to Day 50 of gestation); germ (from yolk sac endoderm) and pregranulosa (derived from the ovarian surface epithelium) cellular migration into and colonization of the ovaries (Days 30-65); clonal expansion of oogonia (Days 35-75); onset of meiosis and arrest (by Day 80) at the dictyate stage of prophase (the first division of meiosis is not completed until ovulation); and ovigerous cord regression and primordial follicle emergence (Days 65-110) [ 1 31 32 33 ] . It seems apparent that germ cells are particularly vulnerable to a metabolic insult when in the phasic transition between mitosis and meiosis I.

  • In this issue of PLoS Biology , one of two related papers exploring the regulation of cohesin in vertebrates shows that phosphorylation of Scc3 (SA2) by Polo-like kinase is apparently sufficient to allow dissociation from chromosome arms, which occurs during prophase [32].


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