Words similar to prohb-egf

Example sentences for: prohb-egf

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It is interesting that the combination of colony hybridization and yeast two-hybrid screens used in this study to identify proteins that interact with the extracellular domain of proHB-EGF yielded independent GAL4-LTBP-3 fusion proteins that all contained these calcium-binding type II EGF-like domains (Fig.
The extracellular domain of proHB-EGF interacts with monkey fibulin-1C (Additional file 1).
3and materials and methods) was tested using the yeast two-hybrid system and found to interact with the extracellular domain of proHB-EGF (Table 1).
The membrane-bound precursor and soluble forms of heparin-binding epidermal growth factor-like growth factor (HB-EGF) contribute to a variety of cellular developmental processes [ 1 ] . The observations of HB-EGF in cell and tissue types have suggested roles for HB-EGF in numerous cellular and tissue events such as: cell movement, extracellular matrix formation, tumor formation and cell adherence [ 1 ] . As described above, the membrane-bound precursor of HB-EGF (proHB-EGF) is also the cell-surface receptor for diphtheria toxin (DT) in DT-sensitive cells [ 2 ] .
Some of these cDNA library clones were transformed into the other yeast host strain, Y187, and tested for β-galactosidase activity as a further check that these clones did indeed contain potential protein-interacting partners for the extracellular domain of proHB-EGF.