Words similar to prodrugs

Example sentences for: prodrugs

How can you use “prodrugs” in a sentence? Here are some example sentences to help you improve your vocabulary:

Because of the high catalytic efficiency and broad substrate specificity, β-lactamases have been extensively used in the ADEPT approach to activate prodrugs of vinca alkaloids [ 27 ] , nitrogen mustard [ 28 29 30 31 32 ] , doxorubicin [ 33 34 35 36 ] and others [ 37 ] . To take advantage of the potent antitumor activity of the CC-1065 class of compounds and the ADEPT approach, we have synthesized β-lactam prodrugs.
Despite ongoing, albeit reduced, viral replication in the animals, selection of resistant HSV with the prodrugs proved difficult.
Due to the slow non-enzymatic degradation of the cephalosporins in solution [ 39 ] , the ratio of toxicity of cephalosporin-containing prodrugs to their corresponding free drugs is generally not very high.
However, some of the prodrugs are very effective against tumors in mouse models.
[ 25 26 ] Oral fluoropyrimidines and oral regimens using prodrugs of 5-FU or inhibitors of dihydropyrimidine dehydrogenase (DPD) which pharmacologically simulate the intravenous continuous infusion administration of 5-FU are currently under clinical evaluation.