Example sentences for: prodrugs

How can you use “prodrugs” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Because of the high catalytic efficiency and broad substrate specificity, β-lactamases have been extensively used in the ADEPT approach to activate prodrugs of vinca alkaloids [ 27 ] , nitrogen mustard [ 28 29 30 31 32 ] , doxorubicin [ 33 34 35 36 ] and others [ 37 ] . To take advantage of the potent antitumor activity of the CC-1065 class of compounds and the ADEPT approach, we have synthesized β-lactam prodrugs.

  • However, some of the prodrugs are very effective against tumors in mouse models.

  • [ 25 26 ] Oral fluoropyrimidines and oral regimens using prodrugs of 5-FU or inhibitors of dihydropyrimidine dehydrogenase (DPD) which pharmacologically simulate the intravenous continuous infusion administration of 5-FU are currently under clinical evaluation.

  • Despite ongoing, albeit reduced, viral replication in the animals, selection of resistant HSV with the prodrugs proved difficult.

  • Due to the slow non-enzymatic degradation of the cephalosporins in solution [ 39 ] , the ratio of toxicity of cephalosporin-containing prodrugs to their corresponding free drugs is generally not very high.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast