Words similar to prodrug

Example sentences for: prodrug

How can you use “prodrug” in a sentence? Here are some example sentences to help you improve your vocabulary:

Antibody-directed enzyme prodrug therapy (ADEPT) [ 1 2 3 4 5 ] is one of the promising new approaches that selectively target tumor cells, thus reducing toxic side effects to patients.
The HL60/TLK286 cell line is resistant to the prodrug TLK286 and derived from the wild-type HL60 by stepwise selection.
Sub-optimal therapy of immunocompetent mice with either VCV or FCV did not readily select for HSV-mutants resistant to either ACV or PCV, suggesting that selection of resistance with either prodrug remains difficult using this system.
Prodrug 2 is expected to be less toxic than its corresponding free drug 1 . However, it is expected that the prodrug will be converted to the potent free drug by β-lactamases localized on the tumor cell surface by an antibody (Figure 2).
Acyclovir has been in part superceded by the oral prodrugs valaciclovir (VCV) and famciclovir (FCV), the latter being the oral version of PCV [ 20 24 ] . No comparative studies of the emergence of resistance following sub-optimal VCV or FCV have been reported and therefore set out to to select for HSV-1 and HSV-2 isolates resistant to ACV and PCV after using prodrug selection.