Example sentences for: prodrug

How can you use “prodrug” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To evaluate efficacy of prodrug treatment in this model, VCV and FCV were provided in the drinking water at 1.0 mg/ml or at 0.2 mg/ml (sub-optimal treatment) for mice infected with either HSV-1 SC16 or HSV-2 SB5.

  • This selective activation of prodrug 2 at the tumor site will lead to enhanced antitumor therapeutic efficacy.

  • Antibody-directed enzyme prodrug therapy (ADEPT) [ 1 2 3 4 5 ] is one of the promising new approaches that selectively target tumor cells, thus reducing toxic side effects to patients.

  • The cytotoxicity of prodrug 2 and its corresponding free drug 1 was tested against U937 leukemia cells, and the results are presented in Table 1. When the drugs were incubated with U937 cells for a period of 48-h, prodrug 2 (IC 50 : 0.9 nM) is 10-fold less toxic than its corresponding free drug 1 (IC 50 : 0.09 nM).

  • The HL60/TLK286 cell line is resistant to the prodrug TLK286 and derived from the wild-type HL60 by stepwise selection.


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