Words similar to prodrug

Example sentences for: prodrug

How can you use “prodrug” in a sentence? Here are some example sentences to help you improve your vocabulary:

Antibody-directed enzyme prodrug therapy (ADEPT) [ 1 2 3 4 5 ] is one of the promising new approaches that selectively target tumor cells, thus reducing toxic side effects to patients.
The preliminary in vitro studies show the prodrug to be less toxic than the free drug.
Acyclovir has been in part superceded by the oral prodrugs valaciclovir (VCV) and famciclovir (FCV), the latter being the oral version of PCV [ 20 24 ] . No comparative studies of the emergence of resistance following sub-optimal VCV or FCV have been reported and therefore set out to to select for HSV-1 and HSV-2 isolates resistant to ACV and PCV after using prodrug selection.
To evaluate efficacy of prodrug treatment in this model, VCV and FCV were provided in the drinking water at 1.0 mg/ml or at 0.2 mg/ml (sub-optimal treatment) for mice infected with either HSV-1 SC16 or HSV-2 SB5.
This selective activation of prodrug 2 at the tumor site will lead to enhanced antitumor therapeutic efficacy.