Example sentences for: probands

How can you use “probands” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • If probands have had more than one ischemic stroke, the most recent is the proband index stroke.

  • Fourteen A alleles were detected in 139 probands (Table 1).

  • Similarly, the frequency of A*03 positivity was significantly increased in Alabama hemochromatosis probands diagnosed before the discovery of HFE [ 21 ] . These observations are consistent with and extend the findings of 21 previously reported case-controlled studies from thirteen countries which demonstrate the significantly increased prevalence of A*03 in persons with hemochromatosis [ 16 ] . The alleles B*07 and B*14 were also more common in the present Alabama probands and in Alabama probands diagnosed before discovery of HFE than in corresponding control subjects [ 21 ] . The present analysis demonstrates that this is attributable largely to the association of B*07 and B*14 with A*03, consistent with observations in persons with hemochromatosis patients from many locations, including Ireland [ 6 ] , Brittany [ 2 32 33 34 ] , Denmark [ 7 8 ] , Sweden [ 9 35 36 ] , Germany [ 10 11 37 38 ] , Portugal [ 30 39 ] , Italy [ 2 40 ] , and Utah [ 20 ] .

  • Absolute or "uncorrected" values of A and B phenotype frequencies in probands, respective frequencies of A and B genes, A and B haplotype frequencies, and occurrence of two-haplotype combinations were calculated after enumeration of the raw data.

  • Probands are not enrolled if any of the following conditions apply: 1) The index stroke is presumed to be iatrogenic - that is, onset of symptoms occurred within 48 hours after an invasive cerebrovascular or cardiovascular procedure, such as coronary artery bypass grafting, a catheter-based procedure on carotid or coronary arteries, carotid endarterectomy, heart valve surgery, or thoracic or thoracoabdominal aortic aneurysm repair.


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