Example sentences for: probands

How can you use “probands” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Twenty-five B alleles were detected in 139 probands (Table 2) [ Additional file 1].

  • A data set that included HLA types in 139 probands and haplotypes in 118 probands was available.

  • In addition, the haplotypes A*01-B*08 and A*02-B*44 significantly associated with CVID and IgGSD in the present study are common in both hemochromatosis probands homozygous for HFE C282Y and control subjects in Alabama [ [ 10 ] ; present study].

  • In several countries in northwestern Europe, however, the percentage of C282Y homozygotes in hemochromatosis case series is greater than 90% [ 33 34 35 37 38 ] . In Queensland, a frequency of C282Y homozygosity of 100% was reported among patients identified by phenotype criteria [ 42 ] . Thus, the selection criterion of C282Y homozygosity in the present study nonetheless resulted in a group of hemochromatosis probands the HFE genotypes of which are similar to those of hemochromatosis patients of northwestern European descent in other studies.

  • A presumptive diagnosis of hemochromatosis was established using an elevated transferrin saturation criterion; each proband was subsequently evaluated for iron overload and its complications [ 21 22 23 ] . All probands in the present study were white adults (> 18 years of age).


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