Words similar to proband

Example sentences for: proband

How can you use “proband” in a sentence? Here are some example sentences to help you improve your vocabulary:

In a preliminary study, we found that, whereas 1 in 10 patients with stroke report having a living affected sibling, only 1 in 50 had an affected sibling living in the same city as the proband [ 52 ] .
Cardiomyopathy attributable to iron overload was not diagnosed in any proband.
For each proband, we collect name, date of birth, gender, race, home address, home phone number, e-mail address, and alternative contact information.
Because a SWISS proband might erroneously believe that a sibling never had a stroke, discordance is considered verified only if the sibling can be contacted for a structured telephone interview and gives negative answers to all 8 items on the Questionnaire for Verifying Stroke-Free Status (QVSFS) (Table 1) [ 57 58 ] . Discordant siblings are excluded if they are deemed unreliable historians in the opinion of the interviewer administering the QVSFS on the basis of global impression of moderate or severe impairment of speech, language, hearing, or memory.
Further investigations are necessary to define the clinical significance of the homoplasmic mtDNA alterations found in the proband and to know whether they may act as secondary mutations, synergistically with a primary defect (either nuclear or mitochondrial) that could affect the mitochondrial function and result in this clinical condition.