Words similar to proapoptotic
Example sentences for: proapoptotic
How can you use “proapoptotic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Size distribution of annexin V-binding MP released from HUVEC after proapoptotic stimulation was similar to that of endothelial MP found in blood [ 1 ] . The small size and the absence of nucleic acids indicate that the analyzed MP are different from apoptotic bodies formed in the terminal stage of apoptosis.
Cytochrome c is then released from the mitochondria into the cytosol, where it interacts with downstream proapoptotic proteins such as Apaf-1 and caspase 9. Activation of these proteins further activates nucleases, such as caspase-activated DNase (CAD), which cause DNA fragmentation.
In our study, the proapoptotic stimulation was the only efficient way to release membrane MP from HUVEC.
Also of interest are genes that are upregulated in both the cancers, including IGFBP3 (insulin-like growth factor binding protein 3), which, interestingly, is thought to have proapoptotic activities [ 14 ] , and GSN (gelsolin), which has a role in cellular motility and acts as both a regulator and effector of apoptosis [ 15 ] . Further xenograft studies of the type presented here could examine the responses of the host tissue to the tumor (using a mouse microarray chip), as well as temporal changes in gene expression within the developing tumor.
Hyal-2-increased TNF susceptibility in L929 cells appears to be associated with 1) Hyal-2 upregulation of the proapoptotic WOX1, 2) Hyal-2 migration to the mitochondria during apoptotic cell death, and 3) the prolonged IκBα degradation and NF-κB activation in Hyal-2-expressing cells stimulated with TNF.
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