Words similar to proapoptotic

Example sentences for: proapoptotic

How can you use “proapoptotic” in a sentence? Here are some example sentences to help you improve your vocabulary:

As summarized in Figure 1, PH-20 induces the expression of proapoptotic p53 and WOX1 [ 9 10 ] and downregulates antiapoptotic matrix inter-α-inhibitor [ 9 ] , thereby enhancing TNF susceptibility in L929 cells.
Tumor suppression by Fhit is not destroyed by mutation of the nucleophilic His96 to Asn, a mutation that specifically reduces k cat [ 2 12 ] . Thus, evidence suggests that the proapoptotic function of Fhit depends on formation of an E-S complex.
In contrast, TGF-β1 protects L929 cells from TNF cytotoxicity by upregulating the expression of antiapoptotic TIAF1, TIF2 and a novel matrix protein [ 11 12 13 14 ] . TGF-β1 blocks PH-20-increased TNF susceptibility [ 15 ] . Likewise, PH-20 inhibits TGF-β1-induced TNF-resistance [ 15 ] . TGF-β1 suppresses PH-20-mediated ERK activation [ 16 ] ; however, the ERK activation is not related with PH-20-increased TNF susceptibility in L929 cells [ 15 ] . Whether the proapoptotic p53 and WOX1 block the function of antiapoptotic TIAF1 and TIF2 is not known.
Apoptosis related molecules, such as Bcl-xS, Bax, and casepase-3, are known to be proapoptotic factors and involved in variety of vessel remodeling processes [ 37 38 39 ] . The initial arrest in Bcl-xS gene expression may momentarily depress apoptosis.
For example, the TNF/TNF receptor-signaling complex activates caspase 8, which leads to the activation and cleavage of Bid, a proapoptotic protein of the Bcl-2 family.