Example sentences for: presynaptic

How can you use “presynaptic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • piccolo (Pico) gene (coding for a presynaptic cytomatrix protein): paradoxically, it is matched in chromosome 12 in Cel2 and in chromosome 5 in MGSCv3.

  • The observed bands may represent kinase anchored directly to the cytoskeleton, perhaps on the presynaptic side, where little gravin staining was found, or anchored to gravin, perhaps on the postsynaptic side.

  • 7), it may be labeling the presynaptic membrane, consistent with reports of PKCβ localization to the presynaptic terminals of NMJs [ 22 23 ] . PKCβ initially associates with the cytoskeleton [ 50 ] . Phosphorylation at two places on the kinase core is required first to activate PKC, and second to release it from its cytoskeletal anchorage.

  • This putative association is strengthened by finding for the first time that targeting of RIα requires the AKAP binding surface [ 17 ] . Yotiao is another AKAP enriched at the NMJ, but appears to bind only RII [ 30 ] . PKA phosphorylates the nAChR when stimulated at the synapse by the neuropeptide CGRP and by adenosine from muscle responding to acetylcholine [reviewed by [ 31 ] ]. This phosphorylation may regulate the degradation of the nAChR [ 32 ] . Consistent with the action at the presynapse, it was shown that PKA facilitation of acetylcholine release is dependent on nerve endplate calcium concentration [ 33 ] . Based on our observation of colocalization with synaptophysin at presynaptic vesicles, RIα may be the isotype that influences this release of neurotransmitter.

  • Intense PKCβ immunoreactivity was found in both postsynaptic and presynaptic regions (fig.


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