Words similar to presynaptic
Example sentences for: presynaptic
How can you use “presynaptic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Nociceptors are specialized primary afferent neurons and the first cells in the series of neurons that lead to the sensation of pain [ 1 2 3 4 5 6 7 8 ] . The receptors in these cells can be activated by different noxious chemical or physical stimuli [ 9 10 11 ] . The essential functions of nociceptors include the transduction of noxious stimuli into depolarizations that trigger action potentials, conduction of action potentials from peripheral sensory sites to synapses in the central nervous system, and conversion of action potentials into neurotransmitter release at presynaptic terminals, all of which depend on ion channels [ 6 12 13 14 15 16 ] . Recent expression cloning has led to the identification of the first pain sensory receptor.
PKC has been suggested to play a role in synapse stability and signal transduction at the NMJ [ 24 ] . When calcium influx through the nAChR occurs, acetylcholine appears to activate PKC phosphorylation of this receptor [reviewed by [ 31 ] ]. Phorbol ester activation of PKC causes loss of synapses and nAChR [ 49 ] . Because the presynaptic PKCβ fluorescence band parallels the nAChR band (see fig.
We found partial overlap of the RIα label with synaptophysin, which labels presynaptic vesicles (fig.
Even though the striated labeling in the muscle fibers appears similar to the striations noted for D-AKAP1 and RIα and is where actin is prevalent, the overlap with the mitochondrial marker (cytochrome c) is poor, in contrast with observations of close overlap in cells [ 29 ] . In the NMJ, the D-AKAP2 pattern is rather diffuse, being present in both postsynaptic and presynaptic vicinities, and appears dissimilar to the mitochondrial pattern.
The observed bands may represent kinase anchored directly to the cytoskeleton, perhaps on the presynaptic side, where little gravin staining was found, or anchored to gravin, perhaps on the postsynaptic side.
Loading...