Words similar to preclinical

Example sentences for: preclinical

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Preclinical studies
Approval for these clinical studies was based on ex vivo transduction data in preclinical animal models [ S8 S9 ] . Essentially, all data on transduction efficiency of FLS was derived using retroviral vectors that express lacZ or beta-galactosidase.
The high purity, unlimited availability, and multipotentiality of hESMPCs will provide the basis for future therapeutic efforts using these cells in preclinical animal models of disease.
In the present experiments, AVP-induced grooming and flank marking behaviors were tested in hamsters exposed to chronic treatment with psychotropic drugs shown in preclinical and clinical studies to be effective in the treatment of OCD [ 20 28 ] . The results show differential responsiveness to these treatments.
Clomipramine is a non-selective re-uptake inhibitor of serotonin, and to some extent norepinephrine [ 21 ] and fluoxetine is a selective serotonin re-uptake inhibitor [ 22 ] . Both of these drugs have proven to be effective in different animals models of OCD [ 23 ] . As an additional control, hamsters were also treated with desipramine, a noradrenergic re-uptake inhibitor [ 24 ] that has been found ineffective in inhibiting OCD in preclinical [ 25 ] and clinical studies [ 26 27 ] .