Words similar to preclinical
Example sentences for: preclinical
How can you use “preclinical” in a sentence? Here are some example sentences to help you improve your vocabulary:
Approval for these clinical studies was based on ex vivo transduction data in preclinical animal models [ S8 S9 ] . Essentially, all data on transduction efficiency of FLS was derived using retroviral vectors that express lacZ or beta-galactosidase.
Animal models can play an essential role in guiding preclinical vaccine development, including in studies of preclinical vaccine safety, vaccine toxicity, and vaccine immunogenicity.
Moreover, anti-TNF-α treatment resulted in a modest inhibition of murine IL-1β production in the diseased joint, which is consistent with previous findings that anti-TNF-α antibody inhibits the generation of IL-1 in collagen-induced arthritis and IL-1, IL-6, and IL-8 in rheumatoid synovial cultures [ 26 27 ] . Our study provides preclinical evidence supporting the use of anti-TNF-α mAb in ameliorating arthritic pathology.
A key to combating the spread of CWD is to put into widespread use a preclinical diagnostic test on live animals.
In this regard, this demonstration that the expression of TGF-βs in the preclinical rat model is unaffected by tamoxifen, 9cRA, or 4-HPR may actually have positive implications, because all three agents are already in clinical use.