Words similar to pre-neoplastic
Example sentences for: pre-neoplastic
How can you use “pre-neoplastic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Loss of Fhit protein is among the earliest known events in the development of a variety of the most common and lethal human malignancies [ 1 ] . Loss of Fhit leads to cells that are deficient in programmed cell death and that form tumors in mice while Fhit reexpression in Fhit-cancer cells reduces tumorigenicity and restores programmed cell death [ 2 3 4 5 6 ] . Infection of Fhit +/- mice with viruses that re-express Fhit reduce cancer occurrence [ 7 ] , apparently by killing pre-neoplastic cells that have lost the wild-type Fhit allele.
However, no tumors, pre-neoplastic changes or other CNS morphologic alterations were detected, suggesting that postnatal aberrant Wnt activation is not sufficient to induce CNS tumorigenesis in mice.
The cerebellar phenotype in these mice was not reported, and it is not clear if the aberrantly proliferating neuroepithelial precursors in their mice represent a pre-neoplastic population.