Example sentences for: pre-neoplastic

How can you use “pre-neoplastic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Loss of Fhit protein is among the earliest known events in the development of a variety of the most common and lethal human malignancies [ 1 ] . Loss of Fhit leads to cells that are deficient in programmed cell death and that form tumors in mice while Fhit reexpression in Fhit-cancer cells reduces tumorigenicity and restores programmed cell death [ 2 3 4 5 6 ] . Infection of Fhit +/- mice with viruses that re-express Fhit reduce cancer occurrence [ 7 ] , apparently by killing pre-neoplastic cells that have lost the wild-type Fhit allele.

  • However, no tumors, pre-neoplastic changes or other CNS morphologic alterations were detected, suggesting that postnatal aberrant Wnt activation is not sufficient to induce CNS tumorigenesis in mice.

  • The cerebellar phenotype in these mice was not reported, and it is not clear if the aberrantly proliferating neuroepithelial precursors in their mice represent a pre-neoplastic population.


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