Example sentences for: pre-mi

How can you use “pre-mi” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The size of the hairpin loop was not specifically evaluated as it appears to be variable in known pre-miRNAs; however it was indirectly assessed, as maximization of stem length concomitantly minimizes terminal loop size.

  • We next aligned the 24 pairs of orthologous Drosophila pre-miRNA sequences and assessed their pattern of nucleotide divergence.

  • First, the mature miRNA can be derived from either arm of a given stem-loop, and many predicted pre-miRNAs fold well on either strand.

  • The starting point for our studies was a reference set of 24 Drosophila pre-miRNA sequences ( let-7 , the 21 originally identified by Lagos-Quintana and colleagues, mir-125 , and a previously undescribed paralog of mir-2 that we named mir-2c [ 9 10 29 ] ). We analyzed this set to derive rules and determine parameters that specifically describe known miRNA genes within anonymous genomic sequence.

  • Mutations do eventually accumulate on the non-miRNA-encoding arm, and orthologous pre-miRNAs from more diverged species will often preserve only the 21-24 nucleotide mature miRNA itself.


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