Words similar to pre-mi

Example sentences for: pre-mi

How can you use “pre-mi” in a sentence? Here are some example sentences to help you improve your vocabulary:

Thus, the terminal loop is the most evolutionary labile portion of pre-miRNA.
This suggested that miRNA genes might be found by folding fixed lengths of conserved sequence to identify ones that display the high degree of relatively continuous helicity characteristic of known pre-miRNAs.
Processing of pri-miRNA into the pre-miRNA stem-loop occurs in the nucleus, while subsequent processing of pre-miRNA into 21-22 mers is a cytoplasmic event mediated by the RNAse III enzyme Dicer [ 17 18 19 20 ] ; Dicer is also responsible for cleavage of long perfectly double-stranded RNA into 21-22 nucleotide fragments during RNA interference (RNAi) [ 2 21 ] . These latter molecules, known as silencing RNA (siRNA), bind to and trigger the degradation of perfectly homologous mRNA molecules via RISC, a double-strand RNA-induced silencing complex containing nuclease activity [ 22 23 ] .
The rationale for defining 'regions' and 'super-regions' came from our observation that RNA folding algorithms would not necessarily identify characteristic pre-miRNA structures if they were folded within the context of longer RNAs, owing to base-pairing with non-miRNA sequence.
First, the loop appears to be the least critical feature of a pre-miRNA, an observation supported by the identification of orthologous insect miRNAs that vary quite significantly in terms of both loop size and sequence (data not shown).