Example sentences for: pparα

How can you use “pparα” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The levels of either PPARα mRNA or PPARβ mRNA are not altered under the same conditions.

  • PPARα is the predominant PPAR subtype expressed in liver, as confirmed presently.

  • Rat G6pc has HNF4α consensus binding sites [ 52 ] . In HeLa cells and HepG2 hepatoma cells, PUFA down regulated G6pc, possibly via inhibition of HNF 4α promoter activity [ 52 ] . In our current mouse experiment, the transcriptional effects of LC-PUFA on G6pc may thus have been HNF4α- or PPARα mediated.

  • The PPARα agonist WY14643 had some saving effect at a high concentration (40 μM), however, the difference was not statistically significant (results not shown).

  • Peroxisome proliferator-activated receptors (PPARs) belong to a group of nuclear receptors which includes steroid, retinoid, thyroid hormone receptors and others [ 19 20 21 ] . There are three types of PPARs: PPARα is found predominantly in the liver, heart, kidney, brown adipose and stomach mucosa, and is important for lipid catabolism.


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