Example sentences for: ppars

How can you use “ppars” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • HNFs may compete with PPARs for binding to DR-1 elements.

  • In spite of dramatic differences in the expression of a variety of PPAR-responsive genes, PPAR gene expression itself was quite constant in all mice analyzed, as previously reported [ 31 ] . This constancy of PPAR expression indicates that differences in the transcription of genes containing a PPRE are likely due to the direct activation of PPARs.

  • Based on the observations that: 1. cholesterol oxides cause PCD but the involvement of MAP kinases remains to be investigated; 2. PPARs are important in atherosclerosis but the effect of PPAR activation on cholesterol oxide induced PCD has not been determined, this study was designed to test if a dysregulation of MAP kinases was associated with the cholesterol oxide induced PCD, and to determine if PPAR activation could modulate the cholesterol oxide induced PCD.

  • 15d-PGJ 2 , 15-deoxy-delta 12, 14-Prostaglandin J 2 ; ERK, Extracellular signal-Regulated Kinase; 4-HNE, 4-hydroxynonenal, MAP kinases, Mitogen-Activated Protein kinases; MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide); PBS, phosphate-buffered saline; PPARs, peroxisome proliferator-activated receptors; RPE, retinal pigment epithelium.

  • In the present work, the focus will be on transcription factors previously identified as mediators of LC-PUFA actions, such as PPARs, SREBP, and HNFs.


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