Words similar to potentiate
Example sentences for: potentiate
How can you use “potentiate” in a sentence? Here are some example sentences to help you improve your vocabulary:
The CR-II domain plays an essential role in the ability of TAF II 135 to potentiate ligand-dependent transactivation by the the receptor for all-trans retinoic acid (RAR) in transfected mammalian cells [ 5, 33].
In certain types of tissues, ethanol has been shown to induce membrane translocation of PKC isoforms through activation of phospholipase A and release of diacylglycerol [ 40 ] . This mechanism, however, does not appear to be significant in our case as ethanol without PMA failed to potentiate IFNg-induced MHCII expression in LS1034 cells.
Maintenance of splanchnic blood flow is important because splanchnic hypoperfusion may play a critical role in the pathogenesis of multiorgan dysfunction syndrome [ 2 3 ] . Mechanical ventilation has been suggested to potentiate the adverse effects of underlying critical illness on splanchnic vasculature and contribute to the development of multiorgan dysfunction syndrome, particularly when 'injurious' ventilatory strategies that produce high end-inspiratory lung volumes are employed [ 3 ] . Experimental studies suggested that mechanical ventilation with considerably high levels of PEEP can lead to splanchnic hypoperfusion and marked reduction in hepatic blood flow [ 4 5 6 ] . Furthermore, PEEP may decrease splanchnic blood flow in patients with no underlying lung disease [ 7 8 ] . Most available evidence regarding the effects of PEEP from animal studies has been extrapolated to humans based on the assumption that the effects of mechanical ventilation on humans and animals are similar.
The rationale, at least in part, for this phase II study comes from pre-clinical data suggesting MTX and LV potentiate the anti-tumor activity of 5-FU.
Caspase 6 is activated by active Caspase 3 and in turn cleaves lamin, resulting in nuclear membrane fragmentation [ 55 ] . FAF interacts with the cytoplasmic domain of the Fas receptor to potentiate Fas-mediated apoptosis [ 56 57 ] . Thus, the up-regulated cell cycle inhibitors and apoptotic proteins clearly favor cell cycle arrest and death.
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