Words similar to potentiate
Example sentences for: potentiate
How can you use “potentiate” in a sentence? Here are some example sentences to help you improve your vocabulary:
These cofactors interact with nuclear receptors in a ligand-dependent manner and enhance transcriptional activation via histone acetylation/methylation and recruitment of additional cofactors such as CBP/p300 [ 89 ] . CBP/p300 has been implicated in the functions of a large number of regulated transcription factors based primarily on physical interaction and the ability to potentiate transcription when overexpressed [ 90 ] . In the case of nuclear receptors, the interaction with CBP/p300 is ligand-dependent and relies on the conserved nuclear receptor functional domain, AF-2 (activation function 2).
We sought to see if Gleevec can potentiate the cell killing effects of cisplatin, the leading chemotherapeutic drug for almost all advanced cancer patients.
This would disrupt the negative control of the receptor and potentiate the Ca 2+response.
For example, in insulin-secreting cell lines, PKC was reported to potentiate K ATP activity [ 11 12 ] , although PKC-dependent inhibition [ 13 ] or inhibition followed by activation [ 14 ] has been also reported.
The rationale, at least in part, for this phase II study comes from pre-clinical data suggesting MTX and LV potentiate the anti-tumor activity of 5-FU.
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