Words similar to potentiate
Example sentences for: potentiate
How can you use “potentiate” in a sentence? Here are some example sentences to help you improve your vocabulary:
In cardiac myocytes, PMA is known to activate K ATP through activation of PKC [ 18 19 20 ] . In insulin-secreting cell lines as well, PKC activation by PMA was shown to potentiate K ATP activity [ 11 12 ] . In the present study, however, the activation of K ATP activity by PMA is independent on activation of PKC for two reasons.
These cofactors interact with nuclear receptors in a ligand-dependent manner and enhance transcriptional activation via histone acetylation/methylation and recruitment of additional cofactors such as CBP/p300 [ 89 ] . CBP/p300 has been implicated in the functions of a large number of regulated transcription factors based primarily on physical interaction and the ability to potentiate transcription when overexpressed [ 90 ] . In the case of nuclear receptors, the interaction with CBP/p300 is ligand-dependent and relies on the conserved nuclear receptor functional domain, AF-2 (activation function 2).
The CR-II domain plays an essential role in the ability of TAF II 135 to potentiate ligand-dependent transactivation by the the receptor for all-trans retinoic acid (RAR) in transfected mammalian cells [ 5, 33].
For instance, addition of glucagon-like peptide-1, TGF-β ligands, or other factors that potentiate β-cell maturation, growth, and insulin secretion [46,47,48] may improve the methods described here.
We sought to see if Gleevec can potentiate the cell killing effects of cisplatin, the leading chemotherapeutic drug for almost all advanced cancer patients.
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