Example sentences for: postulates

How can you use “postulates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • But Stross fails to see the larger context for Microsoft's dominance, and we know that from the get-go, when he begins his book with a pretentious foreword that postulates the similarities between Henry Ford and Bill Gates, a comparison to which he alludes repeatedly over the next 239 pages.

  • The author postulates that Ted hates David because David got married while Ted remained alone.

  • This notion has been widely accepted, and often becomes one of the central postulates of models of duplicated gene evolution [ 3, 7, 26, 27].

  • A survey postulates that it is not necessarily bad to be Canadian.

  • Fas contains a single transmembrane domain and belongs to the tumor necrosis factor (TNF)/nerve growth factor family [ 8 ] . FasL contains a single transmembrane domain and is also a member of the same TNF family [ 9 ] . A soluble form of FasL has been described, but appears to be less capable of inducing apoptosis, when compared with the bound form [ 10 11 ] . The binding of FasL with Fas initiates receptor oligomerization, which recruits Fas-associated death domain (FADD) [ 12 ] . FADD binds procaspase-8 and permits activation of caspase-8 through self-cleavage [ 13 ] . Caspase-8 activates the effector caspases, which commits the cell to the orderly process of apoptosis [ 14 15 ] . In addition, caspase-8 cleaves Bcl-2-interactive-death-agonist (Bid) [ 16 ] . Truncated Bid localizes to the mitochondria and promotes cytochrome c release; this process also serves as a major apoptotic-signaling pathway for Fas [ 16 17 18 ] . Depending upon the amount of caspase-8 that is activated, the predominant pathway can be either Bid cleavage with subsequent mitochondrial release of cytochrome c or activation of the effector caspase pathway [ 18 ] . Resident cells of the kidney express both Fas and FasL and Fas/FasL signaling is functional in these cells [ 19 20 21 22 23 24 ] . A recent review by Ortiz and associates [ 25 ] noted that the combined literature demonstrating participation of Fas/FasL pathway in renal injury essentially fulfilled Koch's postulates.


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