Words similar to postulated
Example sentences for: postulated
How can you use “postulated” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is postulated that different targets of HATs by Tat have different consequences.
He will have had no need to consult the Introduction to discover that Tætel's name is preceded by *because it is “inferred from comparative [place-name] evidence and postulated to occur.”
In many organisms, mannose has been shown to be a substrate for hexokinases whereas 3- O -methylglucose is metabolized poorly, if at all, by hexokinases [ 62 65 ] . As a result, processes that are affected by mannose but not by 3- O -methylglucose have been postulated to be regulated via a hexokinase-mediated pathway(s) [ 19 31 32 ] . By this logic, the fact that seed storage lipid breakdown is repressed by the presence of mannose but not by 3- O -methylglucose could also be interpreted to mean that inhibition of seed storage lipid breakdown occurs via a hexokinase-mediated pathway.
Ogg1 knockout mice possess increased levels of 8-OH-dG in their genome, particularly in the mitochondrial genome, but do not seem to exhibit an increased frequency of malignancies [ 44 45 46 ] . It was postulated that the consequences of 8-OH-dG adducts and Ogg1 deficiency affects mainly cells with high oxygen metabolism and slow proliferation, such as liver cells [ 45 ] . While β-cells were not examined in that study, they certainly exhibit both high oxidative metabolism and a low rate of proliferation, consistent with them being a target for the effects of 8-OH-dG adducts.
Several observations support the assertion that a complex interaction between IL-8 and several other growth factors, cytokines, or other proteins is responsible for these tumor-related events [ 5 9 10 11 12 13 ] . Growth regulated protein alpha (GRO-α), beta (GRO-β), and ENA-78 have been reported to be co-induced with IL-8 in A549 cells stimulated with two proinflammatory cytokines, IL-1β and TNF-α [ 14 ] . This result is consistent with the presence of nuclear factor kappa B (NF-κB) consensus binding sites in the promoter regions of all three genes [ 4 15 ] . In addition, GRO-α and -β are also members of the ELR +CXC cytokine family that are reported to be important mediators of tumorigenesis through their angiogenic properties [ 2 16 ] . They both share one of the IL-8 receptors, CXCR2, which has been postulated to regulate the ELR +CXC chemokine-mediated angiogenesis and resulting-tumorigenesis [ 1 ] . These observations suggest that GRO-α and -β may exhibit expression profiles similar to IL-8.
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